Topic
Intramolecular reaction
About: Intramolecular reaction is a research topic. Over the lifetime, 5015 publications have been published within this topic receiving 138213 citations.
Papers published on a yearly basis
Papers
More filters
••
65 citations
••
TL;DR: This unprecedented tandem reaction between N-substituted alpha-bromoacetamides and Michael acceptors proceeds with good yields and excellent diastereoselectivity to provide the corresponding trisubstituting gamma-lactam systems.
Abstract: A new and highly diastereoselective tandem reaction aza-Michael/intramolecular nucleophilic substitution is presented. This unprecedented tandem reaction between N-substituted α-bromoacetamides and Michael acceptors proceeds with good yields and excellent diastereoselectivity to provide the corresponding trisubstituted γ-lactam systems. An application to the concise synthesis of the tricyclic core of (±)-martinelline alkaloids is also described.
65 citations
••
TL;DR: Generation of an intramolecularly tethered, nonracemic diaryl cuprate followed by its oxidation with ground state oxygen at −78° leads to a biaryl precursor to an ellagitannin this paper.
65 citations
••
TL;DR: Synthese de spiroacetals des systemes dioxa-1,7spiro [5.5] undecane et Dioxa]-1,6spiro as mentioned in this paper [4] decane a partir d'α-hydroxyalkyl-5 furannebutanols-2 et -furannepropanols -2 via la cyclisation acide des alkyl-2 dihydro-3,6 hydroxy-6 w-hydroxyl- et -propyl-2 pyrannones
Abstract: Synthese de spiroacetals des systemes dioxa-1,7spiro [5.5] undecane et dioxa-1,6spiro [4.5] decane a partir d'α-hydroxyalkyl-5 furannebutanols-2 et -furannepropanols-2 via la cyclisation acide des alkyl-2 dihydro-3,6 hydroxy-6 w-hydroxybutyl- et -propyl-2 pyrannones-3
65 citations