Topic
Intussusception (medical disorder)
About: Intussusception (medical disorder) is a research topic. Over the lifetime, 6960 publications have been published within this topic receiving 69403 citations. The topic is also known as: Intussusception (morphologic abnormality) & Intussusception NOS (disorder).
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TL;DR: The strong association between vaccination with RRV-TV and intussusception among otherwise healthy infants supports the existence of a causal relation.
Abstract: Background Intussusception is a form of intestinal obstruction in which a segment of the bowel prolapses into a more distal segment. Our investigation began on May 27, 1999, after nine cases of infants who had intussusception after receiving the tetravalent rhesus–human reassortant rotavirus vaccine (RRV-TV) were reported to the Vaccine Adverse Event Reporting System. Methods In 19 states, we assessed the potential association between RRV-TV and intussusception among infants at least 1 but less than 12 months old. Infants hospitalized between November 1, 1998, and June 30, 1999, were identified by systematic reviews of medical and radiologic records. Each infant with intussusception was matched according to age with four healthy control infants who had been born at the same hospital as the infant with intussusception. Information on vaccinations was verified by the provider. Results Data were analyzed for 429 infants with intussusception and 1763 matched controls in a case–control analysis as well as for ...
927 citations
TL;DR: Adult intussusception is an unusual cause of bowel obstruction and the likelihood of neoplasia, particularly in the colon as a cause, is high and Operative management is thus almost always necessary.
Abstract: Background While intussusception is relatively common in children, it is a rare clinical entity in adults, where the condition is almost always secondary to a definable lesion. Data sources Thirteen cases of intussusception occurring in individuals older than 16 were encountered at our institute between 1981 and 1994. Results Presenting signs/symptoms included recurrent bowel obstruction, intermittent pain, and red blood per rectum. Correct preoperative diagnosis was made in six patients using colonoscopy, flexible sigmoidoscopy, upper gastrointestinal (GI) series and computed tomography (CT). At surgery the lead point was identified in the small intestine in eight cases, in the colon in four cases, and one small intestinal intussusception was considered idiopathic. Twelve patients underwent laparotomy and one patient was both diagnosed and treated by colonoscopy alone. Conclusions Adult intussusception is an unusual cause of bowel obstruction. The likelihood of neoplasia, particularly in the colon as a cause, is high. Operative management is thus almost always necessary.
598 citations
TL;DR: A total of 600 cases, comprising 4 of the authors' cases and 596 others in Japan, was analyzed, and the diagnosis of Meckel's diverticulum was made in only 34 of them, which is very low.
Abstract: A total of 600 cases, comprising 4 of our cases and 596 others in Japan, was analyzed, and the diagnosis of Meckel's diverticulum was made in only 34 of them. The rate of diagnosis was 5.7 per cent, which is very low. The most common complication of this disease was intestinal obstruction, the second most common was intussusception, the third was inflammation, and the fourth was rectal bleeding. Ectopic tissue, present in ninety-three patients, consisted of ectopic gastric mucosa in fifty-eight. 99mTc-P scanning was performed on fifteen patients. In twelve of them ectopic gastric mucosa was observed. However, it was not found in three, all of whom had false-positive scans.
483 citations
TL;DR: Malignancy is associated with intussusception much more frequently than was appreciated in earlier literature and with this in mind, the treatment of choice for all types of int Mussusception in adults is resection without reduction whenever possible.
Abstract: Two important points should be remembered in treating intussusception in adults: 1. 1. Malignancy is associated with intussusception much more frequently than was appreciated in earlier literature. It was associated with 24 per cent of cases of enteric intussusception and 54 per cent of all colonic intussusception in this report. 2. 2. With this in mind, the treatment of choice for all types of intussusception in adults is resection without reduction whenever possible.
451 citations
TL;DR: When an intussusception is encountered in adults, an underlying pathologic process usually can and should be determined for proper management.
Abstract: A review of 25 adult patients with intussusception is reported. Intussusception in adults constituted 16.6% of 150 intussusception cases observed during 1956-1985. The underlying pathologic processes were identified in 23 patients (92%). Etiologically, adult intussusception could be categorized into four groups: (1) tumor-related (13 cases, 52%); (2) postoperative (nine cases, 36%); (3) miscellaneous--Meckel diverticulum (one case, 4%); and (4) idiopathic (two cases, 8%). The tumor-related intussusceptions were caused by benign tumors in five and malignant tumors in eight patients. Postoperative intussusceptions were related to various factors including suture lines, ostomy closure sites, adhesions, long intestinal tubes, bypassed intestinal segments, submucosal edema, abnormal bowel motility, electrolyte imbalance, and chronic dilatation of the bowel. The sites of involvement of intussusception were jejunogastric (one), jejunojejunal (seven), ileoileal (four), ileocolic (10), and colocolic (three patients). Four patients had synchronous multiple (ileoileal and jejunojejunal), four had compound (ileoilealcolic), and two had recurrent intussusceptions. When an intussusception is encountered in adults, an underlying pathologic process usually can and should be determined for proper management.
393 citations