Iodine

About: Iodine is a research topic. Over the lifetime, 8936 publications have been published within this topic receiving 139981 citations. The topic is also known as: I & element 53.

Comparison of the carcinogenic effect of x-irradiation with radioactive iodine on the rat's thyroid.

Abstract: Comparison of the Carcinogenic Effect of X-Irradiation with Radioactive Iodine on the Rat's Thyroid

The response of the thyroid gland in normal human subjects to the administration of thyrotropin, as shown by studies with I131.

Abstract: The actions of thyrotropin in various laboratory animals have been studied in considerable detail. Following its administration the thyroid gland becomes hypertrophied and hyperplastic, the content of protein-bound iodine decreases, but there is an increase in the inorganic iodine fraction. The circulating protein-bound iodine and the basal metabolic rate are elevated. An increased capacity of the gland to fix iodine has been demonstrated by the use of I131. Since none of these methods has been generally applicable to the study of normal human beings, and since relatively pure preparations of the hormone have not been readily available, little information has accumulated regarding the actions of thyrotropin in man. In the present study radioiodine methods originally designed for demonstrating the action of thyroid inhibiting substances were adapted to study the influence of single doses of thyrotropin on the several phases of iodine metabolism in the normal human thyroid gland.

Evidence of thyroid volume increase in normal subjects receiving excess iodide.

Abstract: A prospective study was conducted on 10 normal male volunteers to investigate the effect of the administration of excess iodide on thyroid volume. After 1 week of dietary iodide restriction, all subjects were given daily oral doses (27 mg daily total iodine dose) of licorice lecithin-bound iodine tablets for 4 weeks. Thyroid function studies, total serum iodine concentration, and urinary iodine excretion were monitored. Thyroid volume was measured by high resolution echoscanner before treatment, on the day of the last treatment, and 1 month after the treatment. There was a significant rise in serum TSH levels, with a small decline in serum free T4 concentration during iodide administration; the values remained within the normal range except for two subjects. Serum thyroglobulin levels were increased in parallel with serum TSH levels, which became higher than normal after 1 week of treatment. The volume of the thyroid gland became significantly enlarged after 28 days of iodide intake. When iodide was discontinued, thyroid volume and function returned to baseline levels within 1 month for all subjects. This is the first documentated objective evidence that the compensatory rise in serum TSH in response to iodide administration elicits reversible thyroid hypertrophy in normal subjects.

Study of molecular iodine, iodate ions, iodide ions, and triiodide ions solutions absorption in the UV and visible light spectral bands

Abstract: The paper reports on experimental studies concerning the absorption spectra of molecular iodine and its , I−, anions in the spectral band of 180–600 nm. Values of the absorption cross-sections of the above mentioned substances have been measured, and relations of absorption coefficients to concentrations have been studied. The results obtained demonstrate that the spectral band under consideration is likely to be successfully used for simultaneous real-time detection of substances containing iodine with an absorption method using laser emission sources in the UV and visible light spectral bands.