Iodine

About: Iodine is a research topic. Over the lifetime, 8936 publications have been published within this topic receiving 139981 citations. The topic is also known as: I & element 53.

Treatment of Iodine Deficiency in School-Age Children Increases Insulin-Like Growth Factor (IGF)-I and IGF Binding Protein-3 Concentrations and Improves Somatic Growth

Abstract: Context: Iodine deficiency in utero impairs fetal growth, but the relationship between iodine deficiency and postnatal growth is less clear. Objective: The objective of the study was to determine whether iodine repletion improves somatic growth in iodine-deficient children and investigate the role of IGF-I and IGF binding protein (IGFBP)-3 in this effect. Design, Participants, and Interventions: Three prospective, double-blind intervention studies were done: 1) in a 10-month study, severely iodine-deficient, 7- to 10-yr-old Moroccan children (n = 71) were provided iodized salt and compared with children not using iodized salt; 2) in a 6-month study, moderately iodine-deficient, 10- to 12-yr-old Albanian children (n = 310) were given 400 mg iodine as oral iodized oil or placebo; 3) in a 6-month study, mildly iodine-deficient 5- to 14-yr-old South African children (n = 188) were given two doses of 200 mg iodine as oral iodized oil or placebo. At baseline and follow-up, height, weight, urinary iodine (UI), t...

A Physiological Systems Model for Iodine for Use in Radiation Protection

Abstract: This paper summarizes the biokinetic database for iodine in the human body and proposes a biokinetic model for systemic iodine for use in dose assessments for internally deposited radioiodine. The model consolidates and extends existing physiological systems models describing three subsystems of the iodine cycle in the body: circulating inorganic iodide, thyroidal iodine (trapping and organic binding of iodide and synthesis, storage and secretion of thyroid hormones), and extrathyroidal organic iodine. Thyroidal uptake of inorganic iodide is described as a function of stable iodine intake (Y, µg day−1) and thyroidal secretion of hormonal iodine (S, µg day−1). Baseline parameter values are developed for reference adults with typical iodine intake. Compared with the current systemic biokinetic model of the International Commission on Radiological Protection (ICRP) for occupational intake of radioiodine, the proposed model predicts higher absorbed doses to the thyroid per unit uptake to blood for ve...

Protein-bound iodine by alkaline incineration and a method for producing a stable cerate color.

Abstract: THE proposed method controls the reaction of the iodine monochloride arsenious sulfato-ceric acid catalysis in the quantitative estimation of microgram amounts of iodine. This is accomplished in four steps. First, conditions are adjusted so that the eerie ions in each sample are inactive. Second, conditions are changed, allowing the reaction to proceed simultaneously in each specimen for a determined time interval. Third, the catalysis is halted abruptly. Fourth, a stable cerate compound is produced, so that transmittance measurements can be made without color drift. The proposed method prevents iodine loss from solution during analysis by keeping it stabilized in alkaline medium. Conditions are not made acid until the reaction-controlled introduction of eerie ion. Potassium iodide standards are prepared in 4.0 N sodium carbonate, in which the iodine is kept in a reduced state, with no loss, for periods of more than one year at room temperature. Working standards and blanks are carried through each step o...