Showing papers on "Isopimpinellin published in 1985"

A Reverse Phase Technique for Separating the Linearc Furano Coumarins in Celery

Abstract: A reverse phase method for separating the four linear furanocoumarins psoralen, xanthotoxin, bergapten, and isopimpinellin in celery is described. The photosensitizing compounds, psoralen, xanthotoxin, and bergapten were also quantified in celery blades and leaves. The method utilizes a phenyl-bonded HPLC column with a methanol-water solvent system. This system allows the use of a detection wavelength (225 nm) more appropriate for these linear furanocoumarins than is currently used with normal phase systems.

Identification of psoralen, 8-methoxypsoralen, isopimpinellin, and 5,7-dimethoxycoumarin in Pelea anisata H. Mann.

Abstract: 5.7-dimethoxyeoumarin and isopimpinellin, together with the well-known phototoxic, photo-irritant furanocoumarins psoralen and 8-methoxypsoralen, were isolated and identified from leaves and fruits of pelea anisata H. Mann, a plant whose fruit arc used in the construction of mohikana leis used in parts of the Hawaiian Islands, The presence of presence of phototoxic furanocoumarins would explain the occurrence of photodermatitis in the wearers of the leis.

[Isopimpinellin--a furocoumarin from Heracleum sphondylium with chromosome damaging activity].

Abstract: Effects on chromosomes were studied in human lymphocytes IN VITRO as a result of treatment by isopimpinellin plus UV-A. Isopimpinellin was isolated from HERACLEUM SPHONDYLIUM with centrifugal accelerated layer chromatography (CLC). No induction of sister chromatid exchanges was found. Isopimpinellin plus UV-A exhibited, however, a weak clastogenic potency, which was expressed by an enhancement of the gap and break rates by a factor of 2 to 3. The relation between clastogenic and phototoxic activity of furocoumarins is critically discussed.