Isopropyl alcohol

About: Isopropyl alcohol is a research topic. Over the lifetime, 3064 publications have been published within this topic receiving 27354 citations. The topic is also known as: Rubbing Alcohol & Propan-2-ol.

Using isopropyl alcohol impregnated disinfection caps in the neonatal intensive care unit can cause isopropyl alcohol toxicity.

Abstract: Aim The safety of SwabCap alcohol impregnated disinfection caps was questioned in our unit because of malfunctions in luer access valves. We examined whether SwabCaps affected the integrity of two luer access valves and were associated with alcohol injected into the lines. Methods Our bench test study included seven circuits using SmartSite or CARESITE valves exposed to two environmental temperatures. Passive circuits consisted of a 96-hour contact system using SwabCap without other interventions. Active circuits consisted of nine sham injections during a 24-hour period, with the SwabCap replaced after each injection. The active control circuit used isopropyl alcohol impregnated pads to disinfect valves. Isopropyl alcohol was measured at the extremity of all active circuits by gas chromatography. Results The visual appearance of all SmartSite valves and 67% of the CARESITE valves was changed by SwabCap use. The mean isopropyl alcohol dosages were 52 mmol/L in the SmartSite and 8 mmol/L in the CARESITE at room temperature and 73 and 7 mmol/L, respectively, at 35°C. No alcohol was found in the control circuit. Conclusion The SwabCap altered the valves' appearance and allowed significant amounts of isopropyl alcohol to be injected. It should not be used for neonates without further research.

The radiation chemistry of some of the higher aliphatic alcohols—further studies on radicals trapped at low temperatures1

Abstract: The radiation chemistry of isopropyl alcohol, l-butanol, sec-butyl alcohol, and t-butyl alcohol was investigated in both liquid and solid states. The effect of bleaching with visible and ultraviolet light on free radicals trapped in the low-temperature alcohol samples was studied. The results of these experiments were interpreted in terms of ionic and free radical reactions and applied to the problem of alcohol radiation chemistry in general. (auth)

Jettinggtype defrosting and deeicing agent

Abstract: PURPOSE:A defrosting and de-icing agent, useful for defrosting a car windowpanel in winter, which comprises a mixed solution of a monohydric alcohol, a polyhydric alcohol and water in a specified proportion. CONSTITUTION:A stock solution is prepared by mixing 20-91 parts of a 1-3C monohydric alcohol (methyl alcohol, isopropyl alcohol, etc.). 5-60 parts of 2-4C polyhydric alcohol (ethylene glycol, glycerol, etc.) and 4-20 parts of water. Said stock solution is used for melting and removing ice, snow, frost, etc., on a material, by being jetted by use of a propellant such as CO2, LPG or flon.

Serum determinations in toxic isopropanol ingestion.

Abstract: A toxic dose of isopropyl alcohol was ingested by six male mongrel dogs to evaluate the relationship between acetone production and isopropyl degradation. Maximal serum isopropyl levels were achieved approximately 2 to 3 hours after ingestion of 60 mL of 70% isopropyl alcohol. Acetonemia occurred rapidly in the serum (within 15 minutes of ingestion) and continued to rise after isopropanol levels plateaued. The levels of acetone and isopropanol correlated positively throughout the study model with an r of .54 (P less than .001). It is concluded that there is a positive relationship between acetone production and isopropyl metabolism in the setting of a toxic ingestion of isopropanol. Acetone's persistence as a serum marker may be beneficial in identifying isopropyl hours after a suspected ingestion.