Topic
Isovitexin
About: Isovitexin is a research topic. Over the lifetime, 526 publications have been published within this topic receiving 11525 citations. The topic is also known as: 6-Glucosylapigenin & Isovitexin.
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TL;DR: Six compounds have been isolated from the methanol extract of the aerial parts of Gnidia involucrata (Thymelaeaceae) by chemical and spectroscopic means and their structures were determined on-line by LC/UV/APCI-MSn analysis of the crude extract.
60 citations
TL;DR: This is the first study of the active compositions of azuki beans against α-glucosidase, and two pure flavonoid compounds, vitexin and isovitex in, showed high inhibitory activities.
Abstract: A 70% ethanol extract from azuki beans (Vigna angularis) was extracted further with CH2Cl2, EtOAc and n-BuOH to afford four fractions: CH2Cl2-soluble, EtOAc-soluble, n-BuOH-soluble and residual extract fractions. The EtOAc-soluble fractions showed the highest α-glucosidase inhibitory activity. Two pure flavonoid compounds, vitexin and isovitexin, were isolated (using the enzyme assay-guide fractionation method) from the EtOAc-soluble fractions. We further evaluated the interaction between the flavonoid compounds and α-glucosidase by fluorescence spectroscopy. Vitexin and isovitexin showed high inhibitory activities, with IC50 values of 0.4 mg·mL−1 and 4.8 mg·mL−1, respectively. This is the first study of the active compositions of azuki beans against α-glucosidase.
59 citations
TL;DR: The sum of all the flavone glycosides and soluble phenolic acids in the leaves decreased with increased rate of plant nutrients given in animal manure and with increased crop yield and the major phenylpropanoids showed the same general response to nutrient level.
Abstract: From the leaves of barley, Hordeum vulgare, one new flavone C-glucoside and three known flavone glucosides were isolated and characterized by (1)H and (13)C NMR and MALDI-TOF-MS. The novel flavone C-glucoside was isovitexin 7-O-beta-[6' "-O-(E)-p-coumaroyl]glucoside (6' "-coumaroylsaponarin), and the known compounds were isovitexin 7-O-beta-[6' "-O-(E)-feruloyl]glucoside, isoorientin 7-O-beta-[6' "-O-(E)-feruloyl]glucoside, and tricin 7-O-beta-glucoside. The sum of all the flavone glycosides and soluble phenolic acids in the leaves decreased with increased rate of plant nutrients given in animal manure and with increased crop yield. All of the major phenylpropanoids showed the same general response to nutrient level. The concentration of nitrogen in the leaves was not directly related to nutrient application or to contents of phenylpropanoids.
59 citations
TL;DR: Compound (16) showed good activity against three Candida species and the first full unambiguous NMR assignments for (4), (8) and (9) are reported.
59 citations
TL;DR: In this article, a green and intensified extraction process was used to extract bioactive compounds from passion fruit rinds, which achieved higher global yield, phenolic content, and antioxidant activity than the conventional methods.
58 citations