Isovitexin

About: Isovitexin is a research topic. Over the lifetime, 526 publications have been published within this topic receiving 11525 citations. The topic is also known as: 6-Glucosylapigenin & Isovitexin.

Flavonoid and Flavone C-Glycosides from Dregea volubilis:

Abstract: A new acylated flavone C-glycoside, dregeanin (1) was isolated from the flowers of Dregea volubilis, together with vicenin-2, vitexin, isovitexin, isoorientin, rutin, quercetin, luteolin and apigen...

Production of flavonol and flavone 6-C-glucosides by bioconversion in Escherichia coli expressing a C-glucosyltransferase from wasabi (Eutrema japonicum)

Abstract: To produce flavonol and flavone 6-C-glucosides by bioconversion using recombinant Escherichia coli expressing a C-glucosyltransferase from wasabi (WjGT1). Escherichia coli expressing WjGT1 (Ec-WjGT1) converted flavones (apigenin and luteolin) and flavonols (quercetin and kaempferol) into their 6-C-glucosides in M9 minimal media supplemented with glucose, and released these products into the culture media. Ec-WjGT1 system also converts a flavanone (naringenin) into its C-glucoside at a conversion rate of 60% in 6 h. For scale-up production, apigenin, kaempferol, and quercetin were sequentially fed into the Ec-WjGT1 system at concentrations of 20–50 µM every 15–60 min, and the system was then able to produce isovitexin, kaempferol 6-C-glucoside, and quercetin 6-C-glucoside at an 89–99% conversion rate. The Ec-WjGT1 system quickly and easily produces flavone and flavonol 6-C-glucosides at high conversion rates when using sequential administration to avoid precipitation of substrates.

Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius

Abstract: The total flavonoids of Indocalamus latifolius were evaluated in term of their anti-oxidant and hepatoprotective activities. The results showed that in vitro hepatoprotective and anti-oxidant activities of total flavonoids at doses of 200 and 400 mg/kg and 100 mg/kg, respectively, were comparable to those of the known hepatoprotective drug silymarin at 100 mg/kg. These data were supplemented with histopathological studies of rat liver sections. Seven of the main flavonoid compounds purified by column chromatography using silica gel, sephadex LH-20 and develosil ODS, and determined to be vitexin, orientin, isovitexin, homoorientin, tricin, tricin-7-O-β-D-glucopyranoside and quercetin-3-O-glucopyranoside.

Flavonoids from the roots of two Rhynchosia species used in the preparation of a Zambian beverage

Abstract: High concentrations of flavonoids were found in the roots of Rhynchosia insignis and R heterophylla used for the preparation of the popular Zambian munkoyo beverage. The major flavonoids were isolated and identified by means of fast atom bombardment mass spectroscopy and co-chromatography with authentic standards as vicenin-2, schaftoside, isoschaftoside and an isovitexin derivative (in both species) and, additionally, vitexin, isovitexin and a violanthin-type compound in R heterophylla. As these compounds are yellow to orange-yellow in the concentrations found in the roots, they are likely to be responsible for the yellow coloration of the beverage before fermentation.

Multi-Component HPLC Analysis and Antioxidant Activity Characterization of Extracts from Dipsacus sativus (Linn.) Honck

Abstract: A highly reliable high-performance liquid chromatography method was developed and validated for determining quality of extracts from the leaves of Dipsacus sativus (Linn.) Honck. Under optimum conditions, the chromatography profile of eight compounds was collected, with compound saponarin as marker. The analysis results indicated that saponarin and isovitexin were the main active components. Pharmacological experiments proved that extracts from the leaves showed significant antioxidant activity. This work could serve to validate the usefulness of high-performance liquid chromatography analyses in traditional Chinese medicine.