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Isovitexin

About: Isovitexin is a research topic. Over the lifetime, 526 publications have been published within this topic receiving 11525 citations. The topic is also known as: 6-Glucosylapigenin & Isovitexin.


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Journal Article
TL;DR: The chemical constituents of 95% alcohol extract from Swertia delavayi were isolated and identified as oleanolic acid, gentiopcroside, swertiamarin, daucosterol, isovitexin, isoorientin, and swertiadecoraxanthone-II.
Abstract: Objective To isolate and identify the chemical constituents of 95% alcohol extract from Swertia delavayi. Method The compounds were isolated and purified by column chromatogrphy and their structures were identified by the physicochemical properties and spectral analyses. Result Seven compounds were isolated and identified as oleanolic acid (1), gentiopcroside (2), swertiamarin (3), daucosterol (4), swertiadecoraxanthone-II (5), isovitexin (6), isoorientin (7). Conclusion Compounds 2-7 were isolated from S. delavayi for the first time. While the compound 6 was firstly reported from the genus Swertia.

4 citations

Patent
20 Oct 2005
TL;DR: In this article, the authors proposed a method to provide an efficient preparation method of a flavone C glycoside derivative or its salt having an anti-allergic action, which is easily synthesized in a high yield by using isovitexin and vitexIN which are contained in herbs etc.
Abstract: PROBLEM TO BE SOLVED: To provide an efficient preparation method of a flavone C glycoside derivative or its salt having an antiallergic action. SOLUTION: The flavone C glycoside derivative of formula (1) or its salt is easily synthesized in a high yield by using isovitexin and vitexin which are contained in herbs etc. as raw materials. COPYRIGHT: (C)2006,JPO&NCIPI

4 citations

Journal ArticleDOI
13 Jul 2020
TL;DR: The phytochemical studies here described suggest that flavonoids and terpenoids are the substances that contribute to the antiviral activity of the ethanol extracts within this species.
Abstract: Cissus erosa (Vitaceae), popularly known in Brazil as Cipo-fogo, is a medicinal plant used in the treatment of warts and external ulcers. The present study aimed to evaluate the activity of stems and leaves ethanol extracts of C. erosa against the Dengue and Zika virus by the MTT colorimetric method and to carry on the phytochemical characterization of active extracts by high performance liquid chromatography coupled to mass spectrometry (UPLC-MS). Only the leaves ethanol extract showed anti-Dengue virus activity EC50 18.2 µg/ml (SI > 27.5) and low cytotoxicity for LLCMK2 cells (CC50 > 500 mg/ml). Both extracts (stems and leaves) showed anti-Zika virus activity with EC50 of 45.8 mg/ml and 82.8 mg/ml, respectively. These extracts presented CC50 of 309.2 µg/ml (leaves) and 387.6 µg/ml (stems) to Vero cells. Analysis by CCD and HPLC-DAD detected the presence of triterpenes, steroids, flavonoids and tannins. UPLC-MS analyses of these extracts, allowed the identification of the majority of flavonoids present known as vitexin, isovitexin, orientin, isoorientin and two flavones derivatives, methoxyluteolin-6(8)-C-hexosyl and luteolin-7,4’-di-O-glycosylflavone. The results of the phytochemical studies here described suggest that flavonoids and terpenoids are the substances that contribute to the antiviral activity of the ethanol extracts within this species.

4 citations

Journal ArticleDOI
TL;DR: A new fatty alcohol together with ten known compounds was isolated from the leaves of Terminalia arjuna Roxb as mentioned in this paper, which showed good antileishmanial activity with IC50 values of 9.0 and 2.0 μg/mL, respectively.
Abstract: A new fatty alcohol (1) together with ten known compounds was isolated from the leaves of Terminalia arjuna Roxb. Their chemical structures were established on the basis of physical, chemical, and spectroscopic methods to be identified as (E)-3,5,7,16 tetramethylheptadeca-2-en-1-ol (1), apigenin, luteolin, vitexin, isovitexin, luteolin-3′-glucuronide, gallic acid, methyl gallate, ellagic acid, stigmasterol, and β-sitosterol-3-O-glucoside. Apigenin, vitexin, and isovitexin were isolated for the first time from this species, while luteolin-3′-glucuronide was isolated for the first time from the genus Terminalia. Compound 1 and its acetate derivative (2) showed good antileishmanial activity with IC50 values of 9.0 and 2.0 μg/mL, respectively.

4 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202317
202240
202126
202023
201920
201825