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Keratan sulfate

About: Keratan sulfate is a research topic. Over the lifetime, 1253 publications have been published within this topic receiving 57984 citations. The topic is also known as: keratan sulfate & KS.


Papers
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Journal ArticleDOI
TL;DR: Ablation of the Kera gene resulted in subtle structural alterations of collagenous matrix and did not perturb the expression of other SLRPs in cornea, showing that keratocan plays a unique role in maintaining the appropriate corneal shape to ensure normal vision.

186 citations

Journal ArticleDOI
TL;DR: A new rapid, sensitive, and reproducible method is presented which allows the separation of all known animal glycosaminoglycans in a single monodimensional electrophoresis on cellulose acetate.

185 citations

Journal ArticleDOI
TL;DR: Binding of 125I-TSP to lipids from sheep and human erythrocytes and human platelets resolved on thin layer chromatograms indicates that sulfatides are the only lipids in the membrane which bind TSP.

185 citations

Journal ArticleDOI
TL;DR: The lumican message is expressed at high levels in adult articular chondrocytes but at low levels in the young juvenile, a age-related trend in message level is not, however, common to all tissues in which the lumican gene is expressed.

183 citations

Journal ArticleDOI
TL;DR: A role for glycosaminoglycans that contained O-linked sulfates in the 2 or 3 carbon positions of iduronic acid, e.g., dextran sulfate, pentosan polysulfate, and fucoidan, also had inhibitory activity, which suggests a role for these compounds in inhibiting IGF-I.

180 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202310
202222
20217
20209
201912
201812