Labor Complication

About: Labor Complication is a research topic. Over the lifetime, 185 publications have been published within this topic receiving 1614 citations.

Neonatal Bact. coli Meningitis

Abstract: It was suggested by Iwanoff (1898), and supported by Meyer and Kitai (1924), that the origin of the aberrant endometrial tissue was a serosal metaplasia. This was based on the fact that the entire epithelial apparatus of the female genital tract (endometrium, germinal epithelium of the surface of the ovary, etc.) is derived from the primitive coelomic epithelium of the urogenital fold and is a mere modification of the peritoneum. According to this theory, under the influence of ovarian hormonal stimulation the pelvic peritoneum forms tubular invaginations which sink into the subjacent tissue, and the flat endothelium of the involved peritoneum becomes columnar, thus producing an adenomatous condition. The hypothesis'of serosal metaplasia has received influential suppor, especially for the endometrial cysts of the ovary and endometriosis of the umbilicus, 'laparotomy scars, uterine ligaments, intestine, and recto-vaginal septum. An explanation of the stimulus of metaplasia may be found, in the above case, in a study of the behaviour of epithelium in the presence of inflammation. Inflammation beneath a mucous or serous surface produces an infiltrative proliferation in the adjacent epithelium. This epithelial proliferation is at first a protective process, but it can overstep the limit of physiological hyperplasia by producing epithelial tubules which have all the appearances of glandular invasion. Peritoneal endotheliurn, behaves in the same way, and in the present case, in which a chronic intussusception probably gave rise to such a stimulus, the glandular elements are seen to reproduce the exact structure of normal endometrial glands and stimulate a surrounding strorha which is an exact replica of endometrial stroma. Furthermore, these areas of typical endometrial tissue are seen in the sections to lie in immediate apposition to the hyperplastic tubules which are shown to be derived from the peritoneal endothelium. It would seem that reversions of the epithelium under inflammatory, and perhaps ovarian, stimuli are possible in the adult peritoneum, and that the embryonic cells can reproduce endometrial structure.