Topic
Lambda phage
About: Lambda phage is a research topic. Over the lifetime, 1609 publications have been published within this topic receiving 84675 citations. The topic is also known as: Enterobacteria phage lambda.
Papers published on a yearly basis
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TL;DR: The transformation efficiency of human fibroblast cells by pSV2-gpt DNA trapped in erythrocyte membrane vesicles was less than that of L cells by HSV-TK DNA, but almost the same as that of rat cells byHSV- TK DNA.
22 citations
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16 Jul 2006TL;DR: A 3-dimensional, agent-based model of the lambda-switch gene regulatory system is demonstrated, which displays the regulatory lambda switch behavior observed in E. coli, where proteins regulate their own production.
Abstract: We demonstrate a 3-dimensional, agent-based model of the lambda-switch gene regulatory system, which simulates the interactions of proteins, promoters and operators during the phases of lysogenic and lytic growth in the phage lambda infected bacterium Escherichia coli. Following a decentralized approach, all regulatory mechanisms result from local interactions of the biomolecular agents within a simulated 3D cytoplasm. We show that our model displays the regulatory lambda switch behavior observed in E. coli, where proteins regulate their own production. Our lambda switch simulations provide a versatile testbed for studying gene regulation in silico, complementing in vitro experiments.
22 citations
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TL;DR: Heteroduplexes between the E. coli rrn D operon, obtained from the recombinant plasmid pBK8, and circular Vicia cpDNA revealed homologies in the spacer region as well as in the 16 S and 23 S rRNA region.
22 citations
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TL;DR: Evidence is provided that the target antigen of a given scFv displayed on phages can be detected in an immobilized lambda phage cDNA expression library containing thousands of irrelevant clones.
22 citations
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TL;DR: The sequence of the mutated pyrI gene is reported and it is shown that, during the generation of this pyrBI-bearing phage, six codons from lambda DNA have been substituted for the eight terminal codons of the wild-type gene.
22 citations