Topic
Lamm equation
About: Lamm equation is a research topic. Over the lifetime, 101 publications have been published within this topic receiving 10817 citations.
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TL;DR: A new method for the size-distribution analysis of polymers by sedimentation velocity analytical ultracentrifugation that exploits the ability of Lamm equation modeling to discriminate between the spreading of the sedimentation boundary arising from sample heterogeneity and from diffusion is described.
3,651 citations
TL;DR: It is shown that the least-squares approach ls-g*(s) can be extrapolated to infinite time by considering area divisions analogous to boundary divisions in the van Holde-Weischet method, thus allowing the transformation of interference optical data into an integral sedimentation coefficient distribution G(s).
666 citations
TL;DR: New tools for the analysis of protein self-association by sedimentation velocity are developed, their statistical properties are examined, and considerations for optimal experimental design are discussed.
603 citations
TL;DR: This communication examines an extension to a two-dimensional distribution of sedimentation coefficient and frictional ratio, c(s,f(r), which is representative of a more general set of size-and-shape distributions, including mass-Stokes radius distributions, c (M,R(S)), and sedimentation coefficients-molar mass distributions c( s,M).
507 citations
TL;DR: It is suggested that the global analysis of the approach to equilibrium in a short-column sedimentation equilibrium experiment followed by a high-speed short- column sedimentation velocity experiment can result in sedimentation and diffusion coefficients of very high statistical accuracy.
327 citations