Lanosterol

About: Lanosterol is a research topic. Over the lifetime, 1239 publications have been published within this topic receiving 36737 citations. The topic is also known as: (3β)-lanosta-8,24-dien-3-ol & (3β,20R)-lanosta-8,24-dien-3-ol.

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Journal Article•DOI•

A wolf in sheep's clothing: unmasking the lanosterol-induced degradation of HMG-CoA reductase.

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Hudson W. Coates¹, Andrew J. Brown¹•Institutions (1)

University of New South Wales¹

28 Aug 2019-Journal of Lipid Research

TL;DR: The conversion of the two-carbon acetyl-CoA to the twenty-seven-carbon, tetracyclic cholesterol via the mevalonate pathway is a remarkable feat of anabolic engineering that expends approximately one hundred ATP equivalents and eleven oxygen molecules.

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7 citations

Journal Article•DOI•

A convenient new procedure for the oxidative cleavage of the bile acid and lanosterol side chains

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M. Fetizon¹, F. J. Kakis¹, V. Ignatiadou-Ragoussis¹•Institutions (1)

University of Paris¹

01 Jan 1974-Tetrahedron

TL;DR: In this paper, a new method for the degradation of the side chain of lanosterol and bile acids is described, brought about by the action of molecular oxygen on basic solutions of the phenyl ketones ( 1, 7, and 15 ).

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7 citations

Journal Article•DOI•

Carbon-13 Nuclear Magnetic Resonance Spectroscopy of Naturally Occurring Substances.1,2 Lanosterol and Dihydrolanosterol.

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