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Liquid paraffin
About: Liquid paraffin is a research topic. Over the lifetime, 6185 publications have been published within this topic receiving 52956 citations.
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TL;DR: In this paper, the tribological performance of 2-(N-alkylcarbamoylmethyl)thiobenzo-thiazole as an additive to liquid paraffin has been evaluated.
51 citations
TL;DR: In this article, a high preconcentration method by liquid-liquid extraction using liquid surfactant membranes was developed, which achieved a concentration factor of 570, 820, 750, 970, 860, and 880 for chromium(III), manganese(II), cobalt, nickel, copper, and cadmium, respectively.
51 citations
TL;DR: The results of the present study suggest that rosmarinic acid suppresses oral carcinogenesis by stimulating the activities of detoxification enzymes, improves the status of lipid peroxidation and antioxidants, and downregulates the expression of p53 and bcl-2 during DMBA-induced Oral carcinogenesis.
Abstract: Oral cancer accounts for 40%-50% of all cancers in India. Tobacco and alcohol are the major etiological factors contributing to its pathogenesis. The aim of the present study was to explore the key mechanism behind the inhibitory effects of rosmarinic acid against 7,12-dimethylbenz(a)anthracene (DMBA)-induced oral carcinogenesis by evaluating the status of biochemical markers (lipid peroxidation, antioxidants, and detoxification enzymes) and immunoexpression patterns of p53 and bcl-2 proteins. Oral tumors were developed by painting the buccal pouches of golden Syrian hamsters with 0.5% DMBA in liquid paraffin 3 times a week for 14 weeks. We noticed 100% tumor formation in hamsters treated with DMBA alone, and the tumors were histopathologically confirmed as well-differentiated squamous cell carcinoma. Oral administration of rosmarinic acid (100 mg/kg body wt) to DMBA-treated hamsters completely prevented the tumor formation. In addition, rosmarinic acid significantly returned the status of biochemical and molecular markers to near normal range in DMBA-treated hamsters. The results of the present study suggest that rosmarinic acid suppresses oral carcinogenesis by stimulating the activities of detoxification enzymes, improves the status of lipid peroxidation and antioxidants, and downregulates the expression of p53 and bcl-2 during DMBA-induced oral carcinogenesis.
51 citations
TL;DR: In this article, the friction and wear properties of N-containing heterocyclic compounds (indole, indazole and benzotriazole), which have the same cyclic structure except for the number of N atoms, added to alkylbenzene and to a mixture of liquid paraffin with 2 % wt succinimide dispersant were evaluated using a fourball machine.
Abstract: The friction and wear properties of N-containing heterocyclic compounds (indole, indazole and benzotriazole), which have the same cyclic structure except for the number of N atoms, added to alkylbenzene and to a mixture of liquid paraffin with 2 % wt succinimide dispersant were evaluated using a four-ball machine. The N-hexadecanoylindazole and N-hexadecanoylbenzotriazole were synthesised, and their friction and wear properties in liquid paraffin were also evaluated. X-ray photoelectron spectroscopy (XPS) was used to examine the binding energy of N1s on the rubbed surface. The effect of the presence of a lone electron pair of nitrogens in the compounds on antiwear property is discussed using the theory of molecular orbits.
51 citations
TL;DR: The results suggest a failure in haem biosynthesis and/or an accelerated breakdown of existing haem in adjuvant-induced arthritic rats, which might have been caused by the breakdown of certain haem compounds.
50 citations