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Liquid paraffin
About: Liquid paraffin is a research topic. Over the lifetime, 6185 publications have been published within this topic receiving 52956 citations.
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TL;DR: In this article, the authors investigated physicochemical factors that affect such an enhancing effect and found that the effect was not related to the transmissibility of light through the thin layer but to the properties of the spraying reagent (polarity, viscosity and acidity).
37 citations
TL;DR: Oral administration of curcumin and vitamin E in combination with vitamin E showed significantly attenuated renal dysfunction by increased activity of antioxidant enzymes in kidney, demonstrating strong antioxidant and kidney protective activity compared toCurcumin alone.
Abstract: The present investigation reports the protective effects of curcumin (CMN) and vitamin E against CCl4 induced oxidative stress and nephrotoxicity in rats. The toxicant CCl4 was used to induce nephrotoxicity at a dose of 1 ml/kg as 1:1(v/v) mixture with liquid paraffin twice weekly for 8 weeks. Plasma total protein, albumin, urea and creatinine concentrations were measured to assess the renal function. Antioxidant status in the kidney was estimated by determining the activities of glutathione peroxidase (GPx), glutathione reductase (GR), glutathione-S-transferase (GST), catalase (CAT) and superoxide dismutase (SOD) as well as by histopathological examination. CCl4 caused elevated levels of urea and creatinine while it decreased levels of total protein and albumin in plasma. Furthermore, CCl4 treated rats showed marked depletion of renal endogenous antioxidant enzymes. Oral administration of curcumin (100 mg/kg, daily for 8 weeks) and in combination with vitamin E (three times weekly for 8 weeks) showed significantly attenuated renal dysfunction by increased activity of antioxidant enzymes in kidney. It also increased the concentrations of plasma total protein and albumin, while reducing the concentration of urea and creatinine. Kidney sections of CCl4 induced rats showed deleterious alterations in micro anatomy. However, curcumin and vitamin E treatment prevented kidney damage induced by CCl4. This study reveals that curcumin in combination with vitamin E possesses strong antioxidant and kidney protective activity compared to curcumin alone.
37 citations
Journal Article•
TL;DR: The results suggest antioxidant and hepatoprotective properties of C. fistula during its pretreatment against CCl4 induced hepatotoxicity are suggested.
Abstract: CCl4 alone treatment (0.lml of liquid paraffin/100g body weight, ip) for 7 days followed by 0.l ml of CCl4 (in liquid parafiin/100g body weight, ip) from day 8 till day 14, caused a 16 fold increase in lipid peroxidation and a 50% reduction in catalase and glutathione reductase in liver tissue of rats accompanied by an increase in the activities of transaminases. alkaline phosphatase, lactate dehydrogenase and gamma - glutamyl transpeptidase in serum as compared to liquid paraffin treated control. Pretreatment of ethanolic leaf extract of C. fistula (500mg/kg body weight/day for 7 days) followed by CCl4 treatment (0.1 ml/100g body weight from day 8 till day 14) completely reversed back lipid peroxidation and the activities of catalase and glutathione reductase in the liver tissue towards normalcy. This treatment also reversed the elevated levels of the enzymes in the serum. Ethanolic leaf extract alone treatment did not produce any change in all the parameters studied. The results suggest antioxidant and hepatoprotective properties of C. fistula during its pretreatment against CCl4 induced hepatotoxicity.
37 citations
TL;DR: In this article, the foam properties such as foam stability over time at different temperatures, equilibrium surface tension, and bubble morphology (bubble size) were determined by surface tension measurements and inverted fluorescence microscopy.
37 citations
TL;DR: The CMC of cetomacrogol 1000 was practically unaffected by the addition of salt and the extent of interfacial tension reduction with respect to salt concentration was small when compared to corresponding systems containing ionic surfactants.
37 citations