Topic
Liquid paraffin
About: Liquid paraffin is a research topic. Over the lifetime, 6185 publications have been published within this topic receiving 52956 citations.
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TL;DR: In this article, homogeneous dimethyl formamide (DMF) solutions of CDDP and PGLA were poured into liquid paraffin containing Span 80 as a surfactant, followed by solvent evaporation at elevated temperatures.
32 citations
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TL;DR: A kinetic model, incorporated the effects of the toxicity of organic solvents was developed for two-liquid-phase culture of Taxus cuspidata in the two-stage Taxol production and showed that the proposed kinetic model could fit the experimental data satisfactorily.
31 citations
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TL;DR: In this paper, a dual-level packaging technology was used to obtain phase change materials (PCMs) which possess high thermal conductivity and excellent mechanical property, such as high compressive strength and high shape stability.
31 citations
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TL;DR: Preliminary experiments indicated that while there was no asymmetry potential (A-P) in human cataractous lenses (with high sodium content in the oil chamber), a significant transmembrane potential difference was present across both anterior and posterior surfaces.
31 citations
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TL;DR: Sustained release dosage form of diclofenac sodium containing immediate and controlled release components was designed in this paper, where solid dispersion of immediate release component was prepared using polyvinyl pyrrolidone and mannitol carriers by common solvent method.
Abstract: Sustained release dosage form of diclofenac sodium containing immediate and controlled release components was designed. Solid dispersion of immediate release component was prepared using polyvinyl pyrrolidone and mannitol carriers by common solvent method. Controlled release component was prepared in form of spherical beads by ionotropic gelation technique. The beads were prepared based on dispersing drug in solutions of ionic polysaccharides such as chitosan and sodium alginate. These dispersions were dropped into solutions of counter ions such as tetrasodium pyrophosphate and calcium chloride, respectively. The beads were also prepared using agar by dropping agar-drug hot solution into a mixture of chilled liquid paraffin and water. Then, diclofenac sodium controlled release drug delivery systems were prepared by combining the immediate release and controlled release components in different ratios. The formulations were found to be effective in providing controlled release of drug for a longer period of time. The beads were characterized by scanning electron microscopy and X-ray diffraction studies.
31 citations