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Low protein

About: Low protein is a research topic. Over the lifetime, 8139 publications have been published within this topic receiving 213225 citations.


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Patent
26 Dec 1996
TL;DR: In this paper, a technique for grafting unmodified PEO or any other water-soluble polymers to the surfaces of metals and glasses to form biocompatible surfaces having low protein affinity is provided.
Abstract: Methods for grafting unmodified PEO or any other water-soluble polymers to the surfaces of metals and glasses to form biocompatible surfaces having low protein affinity is provided. One technique includes the steps of: (a) providing a support member having a plurality of hydroxyl or oxide groups attached to a surface of said support member; (b) exposing said surface to a silane coupling agent to cause the silane coupling agent to form a silane layer that is covalently bound to the surface wherein the silane layer comprises a plurality of vinyl groups; and (c) exposing the silane layer to a hydrophilic polymer and causing the silane layer to react with the hydrophilic polymer to covalently bond to the silane layer. Exposure of the silane layer to γ-radiation to induce grafting with low radiation to induce grafting of the hydrophilic polymer to the silane layer. Another technique comprises grafting a silylated hydrophilic polymer or chain having a hydrophobic domain directly to the metal or inorganic surface.

125 citations

Journal ArticleDOI
TL;DR: Larvae receiving the mixed diet exhibited an intermediate level of trypsin activity; it is suggested that the ingestion of algae is necessary for optimal assimilation of the zooplankton component of the diet.
Abstract: The growth, survival, digestive enzyme activity and biochemical composition ofPenaeus japonicus (Bate) larvae and postlarvae were measured under three feeding regimes. Larvae were reared through the protozoeal stages usingChaetoceros gracilis. From the first mysis stage, three feeding regimes were used; (A)C. gracilis plusArtemia sp. nauplii, (B)Artemia sp. nauplii alone or (C)C. gracilis alone. No significant difference was found in growth, survival, protein content or lipid content of postlarvae from the treatments receiving the single-feed type, despite the low protein (7%) and highly unsaturated fatty acid content of the alga. Growth of larvae receiving the mixed diet was significantly higher than in the other treatments. Trypsin activity was more strongly influenced than amylase activity by dietary treatment, and differences in the ratio of these enzymes between treatments suggest independent control of their secretion. Trypsin activity recorded in larvae feeding onC. gracilis was up to six time higher than in larvae feeding onArtemia sp. nauplii, apparently in response to the low protein content of the alga. Larvae receiving the mixed diet exhibited an intermediate level of trypsin activity; it is suggested that the ingestion of algae is necessary for optimal assimilation of the zooplankton component of the diet.

125 citations

Journal ArticleDOI
TL;DR: In this paper, low protein fouling 50 kDa poly(ether sulfone) ultrafiltration membranes were produced by UV-assisted graft polymerization of the monomer 1-vinyl-2-pyrrolidinone by using a dip modification technique without loss of protein rejection.
Abstract: Low protein fouling 50 kDa poly(ether sulfone) ultrafiltration membranes were produced by UV-assisted graft polymerization of the monomer 1-vinyl-2-pyrrolidinone by using a dip modification technique without loss of protein rejection. UV lamps with an emission wavelength maximum of 300 nm and two specially selected UV light filters, benzene and an aromatic polyester film, were used to filter out 254 nm wavelength light which was found to be responsible for severe loss of protein rejection. The modified membranes that performed the best were prepared by using 300 nm lamps and the benzene filter. With increasing degree of grafting, these membranes exhibited up to 20% higher surface wettability (cos ϑ = 0.83−0.89) than the base membrane (cos ϑ = 0.74), which translated into lower irreversible flux loss (−0.05 to 0.03 compared with 0.42). While the protein rejection remained unchanged after modification, the permeability of the membranes decreased from 6.5 to 0.3 l m-2 h-1 (kPa)-1 with increasing degree of gr...

125 citations

Journal ArticleDOI
TL;DR: After a protein deficit, food intake and food preferences show adaptive changes that suggest that compensatory mechanisms are induced to restore adequate protein status, indicating that there are human behavioral strategies present to avoid protein shortage and that these involve selection of savory high-protein foods.

124 citations

Journal ArticleDOI
TL;DR: Researchers revealed a concentration- and temperature-dependent aggregation which was not encountered in 26 sera from patients with multiple myeloma involving other gammaG subgroups, and the gammaG3 cases, however, showed the syndrome at relatively low protein concentrations.
Abstract: Studies on the sera and isolated proteins from 14 patients with gammaG3 multiple myeloma revealed a concentration- and temperature-dependent aggregation which was not encountered in 26 sera from patients with multiple myeloma involving other gammaG subgroups. When the gammaG3 myeloma sera were diluted and characterized by analytical ultracentrifugation, complex formation was minimal. However, when these sera were examined undiluted, marked complex formation was observed. Studies on the isolated proteins, their enzymatic fragments, as well as their heavy and light polypeptide chains localized the aggregating sites to the Fd fragment of the heavy chains. The findings were also documented by acrylamide-gel electrophoresis and capillary tube viscometry.THE HYPERVISCOSITY SYNDROME WAS OBSERVED IN SIX PATIENTS: three with gammaG3 myeloma and three with gammaG1 myeloma. In the latter group extreme protein concentrations appeared essential for the development of the clinical symptoms. The gammaG3 cases, however, because of the aggregation phenomenon, showed the syndrome at relatively low protein concentrations.

123 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20227
2021298
2020300
2019278
2018308
2017306