Topic
Macromolecular Substances
About: Macromolecular Substances is a research topic. Over the lifetime, 576 publications have been published within this topic receiving 42297 citations.
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TL;DR: A new method, based on chemical thermodynamics, is developed for automatic detection of macromolecular assemblies in the Protein Data Bank (PDB) entries that are the results of X-ray diffraction experiments, as found, biological units may be recovered at 80-90% success rate, which makesX-ray crystallography an important source of experimental data on macromolescular complexes and protein-protein interactions.
8,377 citations
TL;DR: This brief review of sequence data from embryogenesis, thrombosis, and lymphocyte help and killing is summarized and attempts to clarify the relationships among the members of this family of cell surface receptors.
4,229 citations
TL;DR: This paper presents a meta-analyses of the macromolecular determinants of reaction rates and volume in a solution and describes the mechanisms leading to these rates and volumes.
Abstract: CONTENTS PERSPECTIVES AND OVERVIEW 28 Nomenclature 30 THEORETICAL CONCEPTS 31 The Effect of Macromolecular C owdin9 on Solution Equilibria 31 The Effect of Macromolecular C owdin# on Reaction Rates 36 The Effect of Macromolecular Crowding on Diffusive Transport of Solutes 37 The Effective Specific Volume of a Macromolecule--What Is It? 40
1,430 citations
TL;DR: To properly assess the physiological role of a particular reaction or set of reactions characterized in vitro, it is important to consider the possible influence of crowding and/or confinement upon the reaction in its physiological milieu.
1,362 citations
1,016 citations