Topic
Mass transfer coefficient
About: Mass transfer coefficient is a research topic. Over the lifetime, 7827 publications have been published within this topic receiving 168354 citations.
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TL;DR: This is the first kLa correlation that has been defined and validated for the cited bioreactor system on a bench-to-pilot scale and can be universally applied to calculate the mass transfer coefficient for any of seven relevant cultivation parameters within an accuracy range of +/− 30%.
Abstract: Background
Among disposable bioreactor systems, cylindrical orbitally shaken bioreactors show important advantages. They provide a well-defined hydrodynamic flow combined with excellent mixing and oxygen transfer for mammalian and plant cell cultivations. Since there is no known universal correlation between the volumetric mass transfer coefficient for oxygen kLa and relevant operating parameters in such bioreactor systems, the aim of this current study is to experimentally determine a universal kLa correlation.
58 citations
TL;DR: In this paper, the mixing and mass transfer performance of a high power agitated pilot scale bioreactor has been characterized using a novel combination of computational fluid dynamics (CFD) and experimental investigations.
58 citations
TL;DR: In this article, the mass transfer coefficient in liquid-liquid slug flow inside a square microchannel (MC-1, aspect ratio 1) and a rectangular microchannel with identical hydraulic diameter (400 µm) were investigated experimentally.
58 citations
TL;DR: In this paper, the authors determined the mass transfer properties of pumpkin (Cucurbita moschata) exposed to air drying, and the results indicated that the activation energy for convective mass transfer is higher than that for mass diffusion.
Abstract: The aim of this work was to determine the mass transfer properties of pumpkin (Cucurbita moschata) exposed to air drying. The drying temperatures tested ranged between 30°C and 70°C, and the kinetic behavior was studied in this temperature band. The samples were analyzed in terms of moisture content, acidity, proteins, lipids, and crude fiber, both in the fresh state and after drying. From the chemical analyses made, it was possible to conclude that drying induces some reductions in acidity, lipids, fibers, and proteins. As to the influence of the drying temperature on the process, it was observed that a temperature rise from 30°C to 70°C led to a 70% saving in drying time. The results obtained by fitting the experimental data to the kinetic models tested allowed concluding that the best model for the present case is Henderson–Pabis, and the worst is Vega–Lemus. Furthermore, in this work, it was possible to determine the values of the diffusion coefficient at an infinite temperature, D
e
0
, and activation energy for moisture diffusion, E
d, which were, respectively, 0.0039 m2/s and 32.26 kJ/mol. Similarly, the values of the Arrhenius constant and the activation energy for convective mass transfer, respectively, h
m
0
and E
c, were also calculated, the first being 3.798 × 108 m/s and the latter 86.25 kJ/mol. These results indicate that the activation energy for convective mass transfer is higher than that for mass diffusion.
58 citations
TL;DR: In this article, the effect of the aqueous and the organic phase flow rates on the overall mass transfer coefficient for both extraction and stripping steps was investigated and compared with predicted values from the resistance in series model.
58 citations