Mass transfer coefficient

About: Mass transfer coefficient is a research topic. Over the lifetime, 7827 publications have been published within this topic receiving 168354 citations.

Mass transfer and nutrient absorption in a simulated model of small intestine.

Abstract: There is an increasing need to understand how food formulations behave in vivo from both food and pharma industries. A number of models have been proposed for the stomach, but few are available for the other parts of the gastrointestinal tract. An experimental rig that simulates the segmentation motion occurring in the small intestine has been developed. The objective of developing such an experimental apparatus was to study mass transport phenomena occurring in the lumen and their potential effect on the concentration of species available for absorption. When segmentation motion was applied the mass transfer coefficient in the lumen side was increased up to a factor of 7. The viscosity of the lumen, as influenced by guar gum concentration, had a profound effect on the mass transfer coefficient. The experimental model was also used to demonstrate that glucose available for absorption, resulting from starch hydrolysis, can be significantly reduced by altering the lumen viscosity. Results suggest that absorption of nutrients could be controlled by mass transfer. Practical Application: To address health-related diseases such as obesity, novel foods that provide advanced functions are required. To achieve the full potential offered by the latest developments in the field of food material science, a fundamental understanding of the behavior of food structures in vivo is required. Using the developed gut model we have demonstrated that absorption of nutrients can be controlled by mass transfer limitations.

Design of biochemical reactors mass transfer criteria for simple and complex systems

Abstract: Biochemical reactors are treated as heterogeneous catalytic reactors in which physical mass transfer completely or significantly controls the overall rate of the process being promoted in the reactor. The treatment used to develop basic design strategies takes into account the special constraints imposed by biological and biochemical phenomena on the systems.