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Medicinal plants

About: Medicinal plants is a research topic. Over the lifetime, 3816 publications have been published within this topic receiving 108681 citations. The topic is also known as: medicinal herbs & medicinal plants.


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Journal Article
TL;DR: Medicinal plants namely A. officinalis and R. mucronata showed anti-HIV potential by inhibiting the virus by 2 different mechanisms and interference with the gp120/CD4 interaction and inhibition of viral Reverse Transcriptase contributed to the overall anti-viral activity in vitro.
Abstract: Medicinal plants namely Ocimum sanctum Linn., Withania somnifera Dunal, Tinospora cordifolia (Willd.) Miers. ex Hook.f. & Thoms., Avicennia officinalis Linn. and Rhizophora mucronata Lam. were screened for anti-HIV activity in the present study. O. sanctum , T. cordifolia , A. officinalis and R. mucronata showed anti-HIV potential by inhibiting the virus by 2 different mechanisms. Interference with the gp120/CD4 interaction and inhibition of viral Reverse Transcriptase (RT) contributed to the overall anti-viral activity in vitro . Among these plants A. officinalis and R. mucronata are mangrove plants and their medicinal properties are rarely reported.

46 citations

Journal ArticleDOI
TL;DR: Two databases have been constructed to facilitate applications of cheminformatics and molecular modeling to medicinal plants, and details of molecular target, IC50 and related measures, and associated botanical species are given.
Abstract: Two databases have been constructed to facilitate applications of cheminformatics and molecular modeling to medicinal plants. The first contains data on known chemical constituents of 240 commonly used Chinese herbs, the other contains information on target specificities of bioactive plant compounds. Structures are available for all compounds. In the case of the Chinese herbal constituents database, further details include trivial and systematic names, compound class and skeletal type, botanical and Chinese (pinyin) names of associated herb(s), CAS registry number, chirality, pharmacological and toxicological information, and chemical references. For the bioactive plant compounds database, details of molecular target(s), IC50 and related measures, and associated botanical species are given. For Chinese herbs, approximately 7000 unique compounds are listed, though some are found in more than one herb, the total number for all herbs being 8264. For bioactive plant compounds, 2597 compounds active against 78...

46 citations

Journal Article
TL;DR: In this article, the results of an ethnobotanical project carried out in the area comprising Utror-Gabral Valleys of upper Swat were analyzed and it was shown that almost 90% of these medicinal plants are sold in the local market in fresh form as the collectors are poor and needy.
Abstract: This paper is based on the results of an ethnobotanical project carried out in the area comprising Utror-Gabral Valleys of upper Swat. The residents of the area use indigenous medicinal plants for curing diseases and also sell some of them in the local market for earning their live hood. About 44 medicinal plants are collected in the area during the months of May, June, July and August. Out of these 44 species collected and marketed, 8 species of medicinal plants are endangered, 8 species are vulnerable and 8 species are rare. Bulk of these medicinal plants are used locally and only Berberis lycium, Bergenia ciliata, Podophyllum hexandrum, Colchicum luteum, Dioscoria deltoides, Viola spp., Pistacia integrimma, Morchella esculenta, Paeonia emodi, Rheum australe, Aconitum hetrophyllum, Valeriana jatamansi, Acorus calamus, Juglans regia, Diospyrus lotus and Bistorta amplexicaulis makes their way to national and international markets. A survey conducted shows that medicinal plants collectors include womenfolk (48.26%), men folk (27.0%) and children (24.74%). Almost 90% of these medicinal plants are sold in the local market in fresh form as the collectors are poor and needy. Some species are cleaned, dried in the sun and stored in plastic bags. The percentage of losses is much higher in the storage because the collectors are unaware about the proper storage methods of these plants. The availability of medicinal plants decreased during the past 20 years. According to aged villagers, medicinal plants were abundant in the vicinities of human settlements some 20 years back. However, the population of medicinal plants drastically decreased due to increased marketing pressure on medicinal plants, lack of job opportunities in the area, non sustainable harvesting methods like digging of whole plant and increased population of the area. The medicinal plants are now collected in large volumes from remote areas of Desan, Ghos, Ladhu, Pala-Shair, Sind, Molat, Gozba, Deej, Tosi and Kagishdin.

46 citations

Journal ArticleDOI
TL;DR: The highly significant and positive correlations between total antioxidant capacity parameters and total phenolic content indicated that the phenolic compounds contributed significantly to the antioxidant activity of the tested plant samples.

46 citations

Journal ArticleDOI
TL;DR: Ethanolic and aqueous extracts of selected Sudanese plants that are traditionally used to treat diabetes highly agree with the ethnobotanical uses of these plants as antidiabetic.
Abstract: Diabetes mellitus is a chronic metabolic disease with life-threatening complications. Despite the enormous progress in conventional medicine and pharmaceutical industry, herbal-based medicines are still a common practice for the treatment of diabetes. This study evaluated ethanolic and aqueous extracts of selected Sudanese plants that are traditionally used to treat diabetes. Extraction was carried out according to method described by Sukhdev et. al. and the extracts were tested for their glycogen phosphorylase inhibition, Brine shrimp lethality and antioxidant activity using (DPPH) radical scavenging activity and iron chelating activity. Extracts prepared from the leaves of Ambrosia maritima, fruits of Foeniculum vulgare and Ammi visnaga, exudates of Acacia Senegal, and seeds of Sesamum indicum and Nigella sativa. Nigella sativa ethanolic extract showed no toxicity on Brine shrimp Lethality Test, while its aqueous extract was toxic. All other extracts were highly toxic and ethanolic extracts of Foeniculum vulgare exhibited the highest toxicity. All plant extracts with exception of Acacia senegal revealed significant antioxidant activity in DPPH free radical scavenging assay. These results highly agree with the ethnobotanical uses of these plants as antidiabetic. This study endorses further studies on plants investigated, to determine their potential for type 2 diabetes management. Moreover isolation and identification of active compounds are highly recommended.

46 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
2023617
20221,438
2021239
2020262
2019227
2018252