Topic
Medicinal plants
About: Medicinal plants is a research topic. Over the lifetime, 3816 publications have been published within this topic receiving 108681 citations. The topic is also known as: medicinal herbs & medicinal plants.
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TL;DR: In vitro and in vivo studies of plants with activity against GIN of goats, focusing on the description of chemical constituents related to this effect are summarized, finding the main plant secondary metabolites associated with anthelmintic effect are condensed tannins, saponin and flavonoids.
Abstract: The gastrointestinal nematodes (GIN) stand out as an important cause of disease in small ruminant, especially on goat farm. Widespread resistance to synthetic anthelminthics has stimulated the research for alternative strategies of parasite control, including the use of medicinal plants. The present work summarizes the in vitro and in vivo studies of plants with activity against GIN of goats, focusing on the description of chemical constituents related to this effect. This review retrieved 56 scientific articles from 2008 to 2018 describing more than 100 different plant species. The most frequently investigated family was Fabaceae (30.7%). Most in vitro studies on the activity of plant extracts and fractions were carried out with of free-living stages nematodes. In vivo studies were conducted mainly with the use of plants in animal feed and generally showed lower effectiveness compared to in vitro assays. The main plant secondary metabolites associated with anthelmintic effect are condensed tannins, saponin and flavonoids. However, the studies with compounds isolated from plants and elucidation of their mechanisms of action are scarce. Herbal medicines are thought to be promising sources for the development of effective anthelmintic agents.
33 citations
TL;DR: Findings provide a useful evaluation of the acceptance of medicinal herb and may serve as a benchmark for future research and evaluation concerning the use of medicinal herbs over time.
33 citations
TL;DR: The findings did not reveal any correlation between antioxidant and anticancer effects thus showing specific targeted action against cancer cell lines and these species could be considered as potential sources of anticancer and antioxidant compounds.
33 citations
12 Mar 2013
TL;DR: In this article, Microtrichia perotitii (Asteraceae) was screened for its phyto contents and analgesic properties using hotplate method with mice.
Abstract: Currently, available drugs for the management of pains, fever and inflammation conditions presents with it many known adverse effects, hence the search for new drugs from plants which hitherto may be harmless to humans. To this end, Microtrichia perotitii (Asteraceae) was screened for its phyto contents and analgesic properties using hotplate method with mice. The result of the preliminary Phytochemical studies revealed the presence of tannins, flavonoids, saponins, alkaloids, carbohydrates and phenolics in the plant as a whole. The analgesic study showed that the aqueous extract of the leaves have significant activity (P<0.05; P<0.001) as compared to morphine sulphate (10 mg/kg) used as a standard drug. The result indicated dose-independed activity. Tannins, flavonoids, alkaloids and saponins have been reported to be responsible for the analgesic and anti-inflammatory activities in many medicinal plants of this family. These results may explain the use of the plant for the management of pains and its related ailments in the locality where it is very common.
33 citations
TL;DR: In this review, recent work on the investigation of selected bioactive Thai medicinal plants is presented and their biological activities against infectious diseases including antimalarial and anti-HIV, are highlighted, as well as their anticancer, antiulcer andAnti-inflammatory properties.
Abstract: It has been estimated that plants are the most important source of medicine for more than 80% of the world’s population. Medicinal plants are a vital source of medication in developing countries. Despite the wealth of human experience and folklore concerning the medicinal uses of plants, proper scientific investigation has only been applied to a small fraction of the world’s plants. This is a cause of grave concern as plant species continue to disappear. A rapid response to this situation is urgently needed to prevent the disappearance of the plant species and the ethnopharmacological knowledge that accompanies them. In this review, recent work on the investigation of selected bioactive Thai medicinal plants is presented. Their biological activities against infectious diseases including antimalarial and anti-HIV, are highlighted, as well as their anticancer, antiulcer and anti-inflammatory properties. The chemical transformations of some selected compounds are discussed.
33 citations