Topic
Medicinal plants
About: Medicinal plants is a research topic. Over the lifetime, 3816 publications have been published within this topic receiving 108681 citations. The topic is also known as: medicinal herbs & medicinal plants.
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TL;DR: In this article, the authors evaluated the antiplasmodial, antimicrobial, anti-Trypanosoma brucei rhodesiense and cytotoxicity activities of the seven medicinal plants of Bhutan selected using an ethno-directed bio-rational approach.
94 citations
TL;DR: An investigation was undertaken to determine the possible mechanisms of action of medicinal plants used for dermatological pathologies, and aqueous extracts of M. comosus exhibited the most potent anti-inflammatory and anti-oxidant activity.
Abstract: An investigation was undertaken to determine the possible mechanisms of action of medicinal plants used for dermatological pathologies. A total of 14 plant species were selected from the readily avail
94 citations
TL;DR: Four species have been thoroughly analyzed in order to discover novel α-glucosidase inhibitors, namely, HintonIA latiflora and Hintonia standleyana (Rubiaceae), Ligusticum porteri (Apiaceae), and Brickellia cavanillesii (Asteraceae).
Abstract: Type II-diabetes mellitus (TII-DM) has been regarded as one of the most important public health problems in all nations in the 21st century. Although allopathic therapies remain the most important for the initial management of TII-DM, herbal remedies have gained wide acceptance for treating this condition. These alternative therapies are particularly valued in countries such as Mexico, rich in medicinal plants strongly attached to the cultural values of the population. Medicinal plants are prized sources of α-glucosidase inhibitors, which delay the liberation of glucose from complex carbohydrates, retarding glucose absorption, and thus controlling the characteristic hyperglycemia of TII-DM. Among the plant species used for treating diabetes in Mexico only 38 have been analyzed for their inhibitory activity of α-glucosidases. Most of these studies, reviewed in the present work, have focused on the evaluation of different types of extracts on the activity of α-glucosidases from diverse sources. Four species have been thoroughly analyzed in order to discover novel α-glucosidase inhibitors, namely, Hintonia latiflora and Hintonia standleyana (Rubiaceae), Ligusticum porteri (Apiaceae), and Brickellia cavanillesii (Asteraceae). Their ethnomedical uses, pharmacological and toxicological studies, chemical composition, and antihyperglycemic principles with α-glucosidase inhibitory activity are summarized.
93 citations
01 Jan 2003
TL;DR: Among 42 extracts, prepared from 14 medicinal plants used in Vietnamese traditional medicine to treat malaria, 24 extracts had antiplasmodial activity by inhibiting the growth of the chloroquine-resistant Plasmodium falciparumstrain FCR-3 with EC50 values less than 10g/ml.
Abstract: Among 42 extracts, prepared from 14 medicinal plants used in Vietnamese traditional medicine to treat malaria, 24 were found to have antiplasmodial activity by inhibiting the growth of the chloroquine-resistant Plasmodium falciparumstrain FCR-3 with EC50 values less than 10g/ml. Each medicinal plant possessed at least one active extract. The methanol extract of Coscinium fenestratumhad the strongest antiplasmodial activity with EC50 value of 0.5g/ml. Activity-guided fractionation led to identification of berberine as the major active constituent.
93 citations