Showing papers on "Methacrylic acid published in 2015"
TL;DR: In this article, the interaction between styrene-acrylate latexes and cement is investigated with emphasis of the charge properties of the polymer particles by means of calorimetry, adsorption measurement, and confocal laser scanning microscope.
169 citations
TL;DR: In this contribution, a variety of innovative semi-interpenetrating polymer network (semi-IPN) hydrogels consisting of Salecan and poly(methacrylic acid) (PMAA) were developed via free radical polymerization for controlled drug delivery.
Abstract: Salecan is a novel linear extracellular polysaccharide with a linear backbone of 1–3-linked glucopyranosyl units. Salecan is suitable for preparing hydrogels for biomedical applications due to its prominent physicochemical and biological profiles. In this contribution, a variety of innovative semi-interpenetrating polymer network (semi-IPN) hydrogels consisting of Salecan and poly(methacrylic acid) (PMAA) were developed via free radical polymerization for controlled drug delivery. The successful fabrication of the semi-IPNs was verified by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), and thermogravimetric (TGA) measurements. Scanning electron microscopy (SEM) and rheology analyses demonstrated that the morphological and mechanical behaviors of the resultant hydrogels were strongly affected by the contents of Salecan and cross-linker N,N′-methylenebis(acrylamide) (BIS). Moreover, the swelling properties of these hydrogels were systematically investigated, and the results indica...
123 citations
TL;DR: In this paper, the authors used graft copolymerization reaction of methacrylic acid (MAA) and itaconic acid (IA) on nanocellulose/nanobentonite (NC/NB) composite using ethyleneglycol dimethacrylate (EGDMA) as crosslinker and potassium peroxydisulfate (KPS) as initiator.
110 citations
TL;DR: The Gg-cl-P(AAm-co-MAA) hydrogel could be a potential adsorbent for the remediation of dyes from industrial wastewater.
91 citations
TL;DR: The microwave-assisted synthesis of gum-ghatti (Gg)-grafted poly(acrylamide-co-methacrylic acid) (AAm- co-MAA) hydrogels for the development of biodegradable flocculants and adsorbents was demonstrated to have potential for use as flocculated and heavy metal absorbents for industrial waste water treatment.
82 citations
TL;DR: A novel potentiometric sensor with high selectivity in addition to sensitivity was developed for the determination of lindane, γ-hexachlorocyclohexane (γ-HCCH), based on the modification of γ -HCCH imprinted polymer film onto the surface of Cu electrode.
76 citations
TL;DR: Aggregation induced emission (AIE) active copolymers P1-P6 with high molecular weights and low polydispersity indices (1.3-1.4) were prepared through copolymerization of N-isopropyl acrylamide (NIPAM) and tetra(phenyl)ethene (TPE)-based acrylate monomers.
Abstract: Aggregation induced emission (AIE) active copolymers P1–P6 with high molecular weights (14 000–17 000) and low polydispersity indices (1.3–1.4) were prepared through copolymerization of N-isopropyl acrylamide (NIPAM) and tetra(phenyl)ethene (TPE)-based acrylate monomers. Copolymers P1–P6 show comparable thermal stability to poly(N-isopropylacrylamide) (PNIPAM), while their glass transition temperatures are higher by 7–9 °C than those of pristine PNIPAM. Copolymers P1–P6 are soluble in common organic solvents as well as in water. They retain a similar thermal sensitivity to PNIPAM, but their lower critical solution temperatures (LCST) are reduced with increase of TPE content. By changing the molar ratio of P1–P6/poly(methacrylic acid) (PMAA) and pH, complexes P1–P6–PMMA were studied by fluorescence spectroscopy and dynamic light scattering (DLS). The complexes are non-emissive in THF, and their fluorescence can be turned on upon addition of water. Moreover, their fluorescence is enhanced with the decrease in pH values due to the formation of interpenetrating polymer networks (IPNs) through inter-polymer hydrogen bonding. Fluorescence spectroscopy and DLS results also reveal that the phase transition behaviour of IPNs upon heating could be significantly modified by pH change. Reduction in the pH value from 7.0 to 4.0 leads to the decrease in LSCT of IPNs by up to 5 °C with respect to PNIPAM. By tuning the pH value to dissociate the formed inter-polymer hydrogen bonds, the formed IPNs would be able to fold cooperatively to a compact structure without a loss of solubility at temperatures below the LCST. Thus, these novel IPNs with AIE active moieties would be used as drug delivery systems, in which the release process could be readily monitored by fluorescence spectroscopy.
71 citations
TL;DR: In this paper, three Keggin-type heteropoly catalysts with different vanadyl species, H4PMo11VO40, HVOPMo12O40, and V2O5/H3PMo 12O40 were used for selective oxidation of methacrolein to methacrylic acid.
67 citations
TL;DR: In this article, a facile method was employed to prepare a durable polymeric layer with pH-triggered switchable surface wettability on cotton fabric for oil/water separation.
62 citations
TL;DR: Gum ghatti-graft-poly(methacrylic acid-aniline) interpenetrating network (IPN) hydrogel was prepared by a two-step aqueous polymerization method.
Abstract: Gum ghatti-graft-poly(methacrylic acid-aniline) interpenetrating network (IPN) hydrogel was prepared by a two-step aqueous polymerization method. First, poly(methacrylic acid) (poly(MAA)) chains were graft co-polymerized onto a Gum ghatti (Gg) backbone via free radical polymerization. Different reaction conditions were optimized in order to incorporate maximum water uptake capacity of the synthesized hydrogel. The synthesized hydrogel network showed a pH-dependent swelling behavior. Second, aniline (ANI) monomer was penetrated through the preformed Gg-g-poly(MAA) network by simple oxidative polymerization method. The homogeneity and distribution of different ions of the cross-linked hydrogels were investigated by the time-of-flight–secondary-ion mass spectrometry chemical imaging technique, and a correlation analysis by color overlay and scatter plot technique. The resulting cross-linked hydrogels’ structure, morphology, and thermal behavior were investigated. Biodegradation studies of the cross-linked hy...
61 citations
TL;DR: In this paper, molecularly imprinted polymers (MIPs) on the surface of magnetic multi-walled carbon nanotubes (MMWCNTs) were prepared using dibenzothiophene (DBT) as template, methacrylic acid (MAA) as functional monomer, ethylene glycol dimethacrylate (EGDMA) as cross-linking agent and ammonium persulfate (APS) as initiator.
TL;DR: In this article, a poly(methacrylic acid)/silver nanoparticles (PMAA/AgNPs) composite was prepared in-situ and characterized by UV-vis spectroscopy, FTIR, TEM, XRD, and EDS.
TL;DR: In this article, a novel mucoadhesive montmorillonite/starch-graft-poly (methacrylic acid) nanocomposite hydrogels (Mt/S-g-PMAA) based on gelatinized wheat starch, an anionic monomer methacryclic acid (MAA), and different amounts of Montmorillonites (MT) as nanoparticles were synthesized according to the conventional grafting reaction mechanism in the aqueous media.
TL;DR: Self-assembled pH-responsive NIR emission micelles entrapped with doxorubicin (DOX) within the cores by the electrostatic interactions for fluorescence imaging and chemotherapy applications are developed.
Abstract: Responsive block copolymer micelles emerging as promising imaging and drug delivery systems show high stability and on-demand drug release activities. Herein, we developed self-assembled pH-responsive NIR emission micelles entrapped with doxorubicin (DOX) within the cores by the electrostatic interactions for fluorescence imaging and chemotherapy applications. The block copolymer, poly(methacrylic acid)-block-poly[(poly(ethylene glycol) methyl ether methacrylate)-co-boron dipyrromethene derivatives] (PMAA-b-P(PEGMA-co-BODIPY), was synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization, and the molecular weight distribution of this copolymer was narrow (Mw/Mn = 1.31). The NIR fluorescence enhancement induced by the phenol/phenolate interconversion equilibrium works as a switch in response to the intracellular pH fluctuations. DOX-loaded PMAA-b-P(PEGMA-co-BODIPY) micelles can detect the physiological pH fluctuations with a pKa near physiological conditions (∼7.52), and showed pH-responsive collapse and an obvious acid promoted anticancer drug release behavior (over 58.8-62.8% in 10 h). Real-time imaging of intracellular pH variations was performed and a significant chemotherapy effect was demonstrated against HeLa cells.
TL;DR: The comprehensive study of variables through experimental design showed that the maximum performance was achieved under these conditions: pH 7, 10 mL sample volume, 15 mg sorbent, 10 min vortex time, 5 min ultrasonic time, 200 μL methanol/acetic acid as eluent, and 5 min desorption time.
Abstract: A molecularly imprinted polymer was selectively applied for solid-phase extraction and diazinon residues enrichment before high-performance liquid chromatography Diazinon was thermally copolymerized with Fe3O4@polyethyleneglycol nanoparticles, methacrylic acid (functional monomer), 2-hydroxyethyl methacrylate (co-monomer), and ethylene glycol dimethacrylate (cross-linking monomer) in the presence of acetonitrile (porogen) and 2,2-azobisisobutyronitrile (initiator) Then, the imprinted diazinon was reproducibly eluted with methanol/acetic acid (9:1, v/v) The sorbent particles were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopy The comprehensive study of variables through experimental design showed that the maximum performance was achieved under these conditions: pH 7, 10 mL sample volume, 15 mg sorbent, 10 min vortex time, 5 min ultrasonic time, 200 μL methanol/acetic acid (9:1, v/v) as eluent, and 5 min desorption time Under optimized conditions, the molecularly imprinted polymer solid-phase extraction method demonstrated a linear range (002–5 g/mL), a correlation coefficient of 0997, and 0005 g/mL detection limit
TL;DR: This study investigates the structural features of porcine gastric mucin in aqueous dispersions and its interactions with water-soluble polymers using isothermal titration calorimetry, turbidimetric titration, dynamic light scattering, and transmission electron microscopy.
Abstract: This study investigates the structural features of porcine gastric mucin (PGM) in aqueous dispersions and its interactions with water-soluble polymers (poly(acrylic acid) (PAA), poly(methacrylic acid) (PMAA), poly(ethylene oxide), and poly(ethylene glycol)) using isothermal titration calorimetry, turbidimetric titration, dynamic light scattering, and transmission electron microscopy. It is established that PAA (450 kDa) and PMAA (100 kDa) exhibit strong specific interactions with PGM causing further aggregation of its particles, while PAA (2 kDa), poly(ethylene oxide) (1 000 kDa), and poly(ethylene glycol) (10 kDa) do not show any detectable effects on mucin. Sonication of mucin dispersions prior to their mixing with PAA (450 kDa) and PMAA (100 kDa) leads to more pronounced intensity of interactions.
TL;DR: A novel pH-thermo dual responsive hydrogel based on salecan and poly(N,N-diethylacrylamide-co-methacrylic acid) semi-interpenetrating polymer networks (semi-IPNs) that may be a promising candidate for drug delivery system is reported.
TL;DR: In this paper, the molar-mass distributions of poly(acrylic acid) (PAA) and poly(methacrylic acids) (PMAA) by size-exclusion chromatography (SEC) are addressed.
Abstract: The accurate characterization of molar-mass distributions of poly(acrylic acid) (PAA) and poly(methacrylic acid) (PMAA) by size-exclusion chromatography (SEC) is addressed. Two methods are employed: direct aqueous-phase SEC on P(M)AA and THF-based SEC after esterification of P(M)AA to the associated methyl esters, P(M)MA. P(M)AA calibration standards, P(M)AA samples prepared by pulsed-laser polymerization (PLP), and PAA samples prepared by reversible addition-fragmentation chain transfer (RAFT) are characterized in a joint initiative of seven laboratories, with satisfactory agreement achieved between the institutions. Both SEC methods provide reliable results for PMAA. In the case of PAA, close agreement between the two SEC methods is only observed for samples prepared by RAFT polymerization with weight-average molar mass between 80 000 and 145 000 g mol−1 and for standards with peak molar masses below 20 000 g mol−1. For standards with higher molar masses and for PLP-prepared PAA, the values from THF-based SEC are as much as 40% below the molar masses determined by aqueous-phase SEC. This discrepancy may be due to branching or degradation of branched PAA during methylation. While both SEC methods can be recommended for PMAA, aqueous-phase SEC should be used for molar-mass analysis of PAA unless the sample is not branched.
TL;DR: In this paper, the inhibition performance of poly (methacrylic acid) (PMAA) and the effect of addition of iodide ions on the inhibition efficiency for mild steel corrosion in 0.5 m H2SO4 solution were investigated in the temperature range of 303 −333 K using electrochemical, weight loss, scanning electron microscopy (SEM), and water contact angles measurements.
Abstract: The inhibition performance of poly (methacrylic acid) (PMAA) and the effect of addition of iodide ions on the inhibition efficiency for mild steel corrosion in 0.5 M H2SO4 solution were investigated in the temperature range of 303–333 K using electrochemical, weight loss, scanning electron microscopy (SEM), and water contact angles measurements. The results show that PMAA is a moderate inhibitor for mild steel in 0.5 M H2SO4 solution. Addition of small amount of KI to PMAA significantly upgraded the inhibition efficiency up to 96.7%. The adsorption properties of PMAA and PMAA + KI are estimated by considering thermodynamic and kinetic parameters. The results reveal that PMAA alone was physically adsorbed onto the mild steel surface, while comprehensive adsorption mode characterized the adsorption of PMAA + KI. Adsorption of PMAA and PMAA + KI followed Temkin adsorption isotherm. The SEM and water contact angle images confirmed the enhanced PMAA film formation on mild steel surface by iodide ions.
TL;DR: The rebinding of the imprinting effect was evaluated in binding experiments, which proved that the β-CD contributed significantly to the enhancement of the recognition affinity and selective adsorption of the MIP.
Abstract: The molecularly imprinted polymer (MIP) based on methacrylic acid functionalized β-cyclodextrin (MAA-β-CD) monomer was synthesized for the purpose of selective recognition of benzylparaben (BzP). The MAA-β-CD monomer was produced by bridging a methacrylic acid (MAA) and β-cyclodextrin (β-CD) using toluene-2,4-diisocyanate (TDI) by reacting the -OH group of MAA and one of the primary -OH groups of β-CD. This monomer comprised of triple interactions that included an inclusion complex, π-π interaction, and hydrogen bonding. To demonstrate β-CD performance in MIPs, two MIPs were prepared; molecularly imprinted polymer-methacrylic acid functionalized β-cyclodextrin, MIP(MAA-β-CD), and molecularly imprinted polymer-methacrylic acid, MIP(MAA); both prepared by a reversible addition fragmentation chain transfer polymerization (RAFT) in the bulk polymerization process. Both MIPs were characterized using the Fourier Transform Infrared Spectroscopy (FTIR), Field Emission Scanning Electron Microscopy (FESEM), and Brunauer-Emmett-Teller (BET). The presence of β-CD not only influenced the morphological structure, it also affected the specific surface area, average pore diameter, and total pore volume of the MIP. The rebinding of the imprinting effect was evaluated in binding experiments, which proved that the β-CD contributed significantly to the enhancement of the recognition affinity and selective adsorption of the MIP.
TL;DR: In this article, the corrosion inhibition of Al in 0.5 M H2SO4 solution by poly(methacrylic acid) (PMAA) alone and in combination with iodide ions was studied at 303-333 K using gravimetric, electrochemical impedance spectroscopy, potentiodynamic polarization, scanning electron microscopy and water contact angle measurements techniques.
TL;DR: In this paper, the authors used a disulfide-containing cross-linker N,N′-bis(acryloyl) cystamine, which endows the capsules with an excellent redox-labile property.
Abstract: Monodisperse poly(vinylcaprolactam) (PVCL)-based capsules are prepared by precipitation polymerization of vinylcaprolactam (VCL) onto dimethyldiethoxysilane (DMDES) emulsion droplets and removal of the DMDES templates by ethanol. Polymer chains in the shells can be cross-linked during the polymerization by disulfide-containing cross-linker N,N′-bis(acryloyl) cystamine, which endows the capsules with an excellent redox-labile property. Versatility of this technique to prepare capsules with diverse components is demonstrated by the copolymerization of methacrylic acid (MAA) and VCL in the shell to prepare poly(vinylcaprolactam-co-methacrylic acid) (P(VCL-co-MAA)) capsules. The disulfide-bonded capsules can degrade efficiently into low molecular weight species (ca. 1200 Da) when the capsules are incubated with 10 mM glutathione (GSH) as the reducing agent. Delivery of the anticancer drug (doxorubicin, DOX) was also investigated in the P(VCL-co-MAA) capsules. The cumulative in vitro release of DOX-loaded caps...
TL;DR: A method of manipulating the absorption rate of a poly(N-isopropylacrylamide) based hydrogel across a wide range by small alterations in the composition is reported, which might be applied to other tissue engineering and regenerative medicine applications where designed biomaterial degradation behavior is needed.
TL;DR: The prepared ion-imprinted polymer particles have an increased selectivity toward Ni(II) ions over a range of competing metal ions with the same charge and similar ionic radius and were applied to the determination of nickel in tomato and some water samples.
TL;DR: A rational strategy for preparing smart oligo(ethylene glycol)-based hybrid microgels loaded with high content of homogeneously distributed preformed magnetic nanoparticles (NPs) (up to 33 wt%).
Abstract: This article reports a rational strategy for preparing smart oligo(ethylene glycol)-based hybrid microgels loaded with high content of homogeneously distributed preformed magnetic nanoparticles (NPs) (up to 33 wt%). The strategy is based on the synthesis of biocompatible multiresponsive microgels by precipitation copolymerization of di(ethylene glycol) methyl ether methacrylate, oligo(ethylene glycol) methyl ether methacrylate, methacrylic acid, and oligo(ethylene glycol)diac-rylate. An aqueous dispersion of preformed magnetic NPs is straightforwardly loaded into the microgels. Robust monodisperse thermoresponsive magnetic microgels are produced, exhibiting a constant value of the volume phase transition temperature whatever the NPs content. The homogeneous microstructure of the initial stimuli-responsive biocompatible microgels plays a crucial role for the design of unique well-defined ethylene glycol-based thermoresponsive hybrid microgels.
TL;DR: The applicability of prepared polymer-based monolithic column for potential food safety applications was demonstrated by analyzing five aflatoxins and three phenicol antibiotics using the selected poly(lauryl methacrylate-co-MAA- co-EDMA) monolith column.
TL;DR: Results evidence a nonideal brush behavior of p(MA-N) and p(N-AA) and their microphase segregated shell structure, which supports some of the conclusions recently formulated from approximate self-consistent mean-field computations.
Abstract: Particles consisting of a glassy poly(methyl methacrylate) core (ca. 40 nm in radius) decorated with a poly(N-isopropylacrylamide) anionic corona are synthesized using either methacrylic acid (MA) or acrylic acid (AA) as reactive comonomers in the shell. The different reactivity ratios of MA and AA toward N-isopropylacrylamide originates p(MA-N) and p(N-AA) particles with carboxylate charges supposedly located, preferentially, in the close vicinity of the core and at the shell periphery, respectively. The corresponding swelling features of these nanoparticles are addressed over a broad range of pH values (4 to 7.5), NaNO3 concentrations (3 to 200 mM), and temperatures (15 to 45 °C) by dynamic light scattering (DLS) and small angle neutron scattering (SANS). DLS shows that the swelling of the particle shells increases their thickness from ∼10 to 90 nm with decreasing temperature, ionic strength, or increasing pH, with the effect being more pronounced for p(N-AA) whose lower critical solution temperature is...
TL;DR: In this paper, reversible addition-fragmentation chain transfer (RAFT) copolymerizations of methacrylic acid N-hydroxysuccinimide ester and cyclic N-vinylamide derivatives (N-vinylpyrrolidone, N-vinylonpiperidone and N -vinylcaprolactam) were successfully performed with methyl 2-(ethoxycarbonothioylthio)propanoate as chain transfer agent (CTA).
Abstract: Reversible addition–fragmentation chain transfer (RAFT) copolymerizations of methacrylic acid N-hydroxysuccinimide ester and cyclic N-vinylamide derivatives (N-vinylpyrrolidone, N-vinylpiperidone, and N-vinylcaprolactam) were successfully performed with methyl 2-(ethoxycarbonothioylthio)propanoate as chain transfer agent (CTA). Effects of different reaction parameters, such as solvent type, temperature, and CTA-to-initiator (C/I) ratio, were studied to optimize the polymerization conditions in order to obtain copolymers with variable chemical composition, controlled molecular weight, and narrow polydispersity index (PDI). The solvent type has a high impact on the polymerization reaction, and a high C/I ratio decreases polydispersity as well as conversion. Increased steric hindrance through an enlarged lactam ring offsets the monomer reactivity. The controlled character of RAFT polymerization was evidenced by the low PDI of the copolymers and a linear relationship between conversion and molecular weight. B...
TL;DR: In this article, a magnetic hydrogel for the guided release of sunitinib malate (SUM), an anticancer drug, is presented, where particles of magnetite have been encapsulated during the polymerization process, followed by epoxide ring opening on the nanospheres' surface, in order to obtain a restricted access material with low protein adsorption ability and improved biocompatibility.
Abstract: The aim of the present work was the preparation of a magnetic hydrogel for guided release of sunitinib malate (SUM), an anticancer drug. Precipitation polymerization method has been employed in order to synthesize the hydrogel, using methacrylic acid (MAA), ethylene glycol dimethacrylate (EGDMA), glycidyl methacrylate (GMA) and 2,2′-azobisisobutyronitrile (AIBN) as monomer, cross-linker, pro-hydrophilic monomer and initiator, respectively. To confer magnetic responsiveness, particles of magnetite have been encapsulated during the polymerization process, followed by epoxide ring opening on the nanospheres' surface, in order to obtain a restricted access material (RAM) with low protein adsorption ability and improved biocompatibility. The successful introduction of magnetite has been confirmed through FT-IR and TG analyses, while protein adsorbing tests have been conducted to verify the RAM features. Furthermore, swelling properties have been evaluated before and after epoxide ring opening. Finally, in vitro tests have been performed to evaluate the release profile and cytotoxic effect on ARO, WRO, HeLa and MCF-7 cell lines.
TL;DR: In this article, a polymerizable Graphene Oxide (Graphene oxide Monomer, GOM) was synthesized through attaching vinyl groups onto graphene oxide sheets and copolymeized with methacrylic acid in different ratios.
Abstract: A polymerizable Graphene Oxide (Graphene Oxide Monomer, GOM) was synthesized through attaching vinyl groups onto graphene oxide sheets. GOM was copolymeized with methacrylic acid in different ratios. Obtained nanocomposites were characterized by FT-IR, XRD, SEM and EDX to study their properties. Naproxen was entrapped in these pH-sensitive nano-carriers and the in vitro release profiles were established in both enzyme-free simulated gastric and intestinal fluids (SGF, pH 1) and (SIF, pH 7.4) respectively. It was observed that the drug release in SIF was higher, hence the prepared nanocomposite could be considered as a suitable carrier for colon specific drug delivery.