Topic
Methacrylic acid
About: Methacrylic acid is a research topic. Over the lifetime, 13058 publications have been published within this topic receiving 173201 citations. The topic is also known as: α-Methacrylic acid & 2-Methylacrylic acid.
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TL;DR: In selectivity study, it was found that imprinting results increased affinity of the material toward Zn(2+) ion over other competitor metal ions with the same charge and close ionic radius.
61 citations
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11 Jul 2017
TL;DR: Cytotoxicity studies demonstrated that DOX-loaded nanoparticles are highly active against Hela cells and more effective than free DOX of an equivalent dose, and a cellular uptake study revealed that SiO2-PMAA-b-PNIPAM nanoparticles could successfully deliver DOX molecules into the nuclei ofHela cells.
Abstract: A pH and thermal dual-responsive nanocarrier with silica as the core and block copolymer composed of poly(methacrylic acid) (PMAA) and poly(N-isopropylacrylamide) (PNIPAM) as the shell was prepared by surface-initiated reversible addition–fragmentation chain-transfer (SI-RAFT) polymerization. The resulting SiO2-PMAA-b-PNIPAM particles dispersed individually in an aqueous solution at a high pH and a low temperature but reversibly agglomerated under acidic conditions or at elevated temperatures. These dual-responsive nanoparticles were used as carriers to deliver the model drug doxorubicin (DOX) with unusually high entrapment efficiency and loading content, which is due to the small size (15 nm), light weight of the cores, and high graft density (0.619 chains/nm2) achieved by SI-RAFT polymerization. The release rate was controlled by both the pH and temperature of the surrounding medium. Moreover, these particles selectively precipitated at acidic conditions with increased temperature, which may enhance the...
61 citations
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TL;DR: In this paper, Fourier transform infrared (FTi.r) and X-ray photoelectron spectroscopy (XPS) were used to study interpolymer interactions in various complexes.
61 citations
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TL;DR: It was proved that the obtained MIP with introduced method was much better than that prepared in methanol as porogen and could be used as an adsorber for extraction and determination of pyridoxine in real and synthetic samples.
61 citations
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14 Aug 1997TL;DR: In this article, an associative polymeric rheology modifier prepared by polymerization of a C1-C6 alkyl ester of acrylic acid and/or a C 1-C 6 alkyls ester or a methacrylic acid was presented.
Abstract: The present invention relates to acrylate-based, associative polymeric rheology modifier prepared by polymerization of a C1-C6 alkyl ester of acrylic acid and/or a C1-C6 alkyl ester of methacrylic acid, a monomer chosen from a vinyl-substituted heterocyclic compound containing at least one of a nitrogen or sulfur atom, (meth)acrylamide, a mono- or di- (C1-C4)alkylamino (C1-C4)alkyl (meth)acrylate, a mono or di-(C1-C4)alkylamino (C1-C4)alkyl (meth)acrylamide, and an associative monomer.
61 citations