Topic
Methyl vinyl ketone
About: Methyl vinyl ketone is a research topic. Over the lifetime, 1510 publications have been published within this topic receiving 26839 citations. The topic is also known as: 3-buten-2-one & gamma-oxo-alpha-butylene.
Papers published on a yearly basis
Papers
More filters
TL;DR: In this paper, the quantitative kinetics of the reactions of acrylonitrile and methyl vinyl ketone with ethyl acetoacetate and 2,4-pentanedione in basic solut...
Abstract: The quantitative kinetics of the reactions of acrylonitrile and methyl vinyl ketone with ethyl acetoacetate and 2,4-pentanedione, and those of acrylonitrile with ethanol and methanol in basic solut...
9 citations
TL;DR: In this article, a convenient synthetic method for some functionalized isoprenes employing 1-bromo-2-phenylthioethane and ethyl acetoacetate as starting materials is reported.
Abstract: A convenient synthetic method for some functionalized isoprenes employing 1-bromo-2-phenylthioethane and ethyl acetoacetate as starting materials is reported. It has also been found that the dienes thus obtained gave functionalized limonene analogs by Diels–Alder reaction with methyl vinyl ketone.
9 citations
TL;DR: The 1,4-addition of the enolate generated from α-methylated acetoacetate incorporated at C-4 of methyl 6-deoxy-2,3-di- O -( tert -butyldimethylsilyl)-α- d -glucopyranoside to methyl vinyl ketone, followed by aldol condensation of the resulting 1, 4addition product under two base-mediated conditions, provided 4-O-functionalized d-glucose derivatives with high diastereoselectivity as mentioned in this paper.
9 citations
TL;DR: In this paper, the copper-catalyzed conversion of exo-cyclic enamines with methyl vinyl ketone yields spirocyclic products 6a-c in a sequence of Michael and aldol reaction.
Abstract: The copper-catalyzed conversion of exo-cyclic enamines 4a-c with methyl vinyl ketone (2) yields spirocyclic products 6a-c in a sequence of Michael and aldol reaction. The application of the chiral auxiliary L-valine diethylamide results in the formation of quaternary stereocenters with high enantiomeric excess. The configuration of intermediate imine 5a is determined to be S. Thus, exo-cyclic enamines 4 yield S-configured spiroketones 6, whereas, as shown for spiroketone ent-6c, reaction of endo-cyclic enamines such as 1 generates the opposite configuration in the products applying the same auxiliary L-valine diethylamide 9.
9 citations
TL;DR: In this article, the synthesis of α-ambrinol was successfully accomplished by cyclization of dihydroγ-ionone ethylene acetal which was prepared by the titanium(IV)-promoted reaction of 3,3-dimethyl-1-trimethylsiloxycyclohexene with methyl vinyl ketone, followed by exo-methylenation with triphenylphosphonium methylide.
Abstract: Synthesis of α-ambrinol was successfully accomplished by cyclization of dihydro-γ-ionone ethylene acetal which was prepared by the titanium(IV)-promoted reaction of 3,3-dimethyl-1-trimethylsiloxycyclohexene with methyl vinyl ketone ethylene acetal followed by exo-methylenation with triphenylphosphonium methylide.
9 citations