Topic
Methylglyoxal
About: Methylglyoxal is a research topic. Over the lifetime, 2844 publications have been published within this topic receiving 102037 citations. The topic is also known as: acetylformaldehyde & pyruvaldehyde.
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TL;DR: In this paper, the anti-glycation activity of four kinds of beans including mung beans, black beans, soybeans and cowpea was evaluated in a bovine serum albumin (BSA)-glucose model and the inhibitory activities of extracts of the four beans were found to be highly correlated with their total phenolic contents.
211 citations
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TL;DR: The receptor for A GEs, RAGE, is important in development of CKD, but its interaction with AGEs in vivo remains enigmatic; other ligands and ternary complexation may be influential.
209 citations
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TL;DR: Aminoacetone would appear to be an endogenously occurring amine with a Km for metabolism by SSAO far lower than other aliphatic and aromatic biogenic amines examined previously as potential physiological substrates for the human vascular enzyme.
207 citations
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TL;DR: S-Formylglutathione rather than formate is formed from formaldehyde and reduced glutathione in the reaction catalyzed by purified formaldehyde dehydrogenase, which is not strictly NAD-specific; NADP can be used although NADP has a much higher Km value than NAD, especially at high pH values.
205 citations
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TL;DR: DJ-1 is the first protein deglycase that repairs proteins from glycation by glyoxals, which constitutes most glycation damage, and is established as a major anti-glycation and anti-aging protein.
205 citations