Topic
Miscibility
About: Miscibility is a research topic. Over the lifetime, 5521 publications have been published within this topic receiving 133547 citations. The topic is also known as: miscible.
Papers published on a yearly basis
Papers
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TL;DR: IR spectroscopy and PXRD are sensitive to changes in local chemical environments and local structure, which makes them especially useful in elucidating the nature of miscibility in binary mixtures when DSC results are inconclusive or variable.
Abstract: Purpose
To evaluate drug-polymer miscibility behavior in four different drug-polymer amorphous solid dispersion systems, namely felodipine-poly(vinyl pyrrolidone) (PVP), nifedipine-PVP, ketoconazole-PVP, and felodipine-poly(acrylic acid) (PAA).
181 citations
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TL;DR: It was found that hot-melt extrusion of carbamazepine and Soluplus is feasible on a single-screw hot-Melt extruder without the addition of plasticizers, and thermodynamic models obtained are in agreement with the findings of the HME processing, encouraging therefore their further application in theHME process development.
181 citations
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TL;DR: In this article, a new criterion is proposed based on the classical Huggins equation and the huggins coefficient K(m) in the blends, which is reasonable and suitable to predict polymer-polymer miscibility by the viscometry method.
180 citations
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TL;DR: In this paper, the effect of end groups (2OH, 1H, 1CH 3 and 2CH 3 ) of poly(ethylene glycol) on the miscibility and crystallization behaviors of binary crystalline blends of PEG/poly( l -lactic acid) (PLLA) were investigated by differential scanning calorimetry (DSC) and polarizing optical microscopy (POM).
179 citations
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TL;DR: In this paper, the thermal properties of Chitosan acetate with polyvinyl alcohol (PVA) were investigated by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and dynamic mechanical analysis (DMA).
178 citations