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Morpholine

About: Morpholine is a research topic. Over the lifetime, 5411 publications have been published within this topic receiving 51063 citations. The topic is also known as: diethylene imidoxide & diethylene oximide.


Papers
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Journal ArticleDOI
TL;DR: Results indicated that most of the tested compounds showed moderate to good activity comparable to indomethacin, and compound 16 with additional morpholine ring beside the thiophene ring is considered as a promising compound for further modification to obtain clinically useful anti-inflammatory agent.

24 citations

Journal ArticleDOI
TL;DR: In this paper, a convenient and efficient synthetic method for the construction of morpholine and piperazine derivatives in moderate to good yields was established, and a plausible mechanism involving the cascade cyclization and isomerization to produce the six-membered ring was proposed and supported by deuterium labeling experiments.
Abstract: A convenient and efficient synthetic method for the construction of morpholine and piperazine derivatives in moderate to good yields was established. The reaction proceeds smoothly with 1.0 mol% gold catalyst loading. A plausible mechanism involving the cascade cyclization and isomerizations to produce the six-membered ring was proposed and supported by deuterium labeling experiments.

24 citations

Journal ArticleDOI
TL;DR: In this paper, resonators coated with various compositions of poly(styrene-co-chloromethyl styrene) reacted with morpholine as adsorption sites were fabricated for simply but accurately monitoring HCl gas in air.
Abstract: Quartz resonators coated with various compositions of poly(styrene-co-chloromethyl styrene) reacted with morpholine as adsorption sites were fabricated for simply but accurately monitoring HCl gas in air. The exposure of all resonators to HCl gas irreversibly decreased the oscillation frequencies, indicating that these devices can be used for one-shot detection of HCl gas. The chemical structure and composition of the copolymer affected the sensitivity. The largest sensitivity was obtained for the copolymer having 40.0 mol% CMSt composition cross-linked with 5.0 mol% DVB. The sensitivity was 0.1 ppm/Hz for 10-min sensor operation, demonstrating a ppm level of HCl detection, although great interference was produced by changes in the humidity.

24 citations

Journal ArticleDOI
Wenfang Wang1, Qiangsheng Sun1, Daqian Xu1, Chungu Xia1, Wei Sun1 
TL;DR: An iron complex with a chiral aminopyridine N4 ligand bearing strong electron-donating and bulky morpholine groups on the ligand was synthesized and characterized in this paper.
Abstract: An iron complex with a chiral aminopyridine N4 ligand bearing strong electron-donating and bulky morpholine groups on the ligand is synthesized and characterized. The iron complex serves to efficiently catalyze the asymmetric epoxidation of various olefins by employing aqueous hydrogen peroxide as the green oxidant, providing the corresponding epoxides in good to excellent yields and enantioselectivities (up to 93 % yield and 99.9 % ee). Owing to the introduction of morpholine functional groups on the ligand, the Fe-catalyzed reaction can proceed with a catalytic amount of the carboxylic acid partner (3 mol %).

24 citations

Journal ArticleDOI
TL;DR: The asymmetric oxidation of sulfides to sulfoxides was realized with layered double hydroxides (LDH)-supported OsO4 catalyst using N-methyl morpholine Noxide as co-oxidant and (DHQD)2PHAL (hydroquinidine 1,4-phthalazinediyl diether) as a chiral ligand in good yields albeit moderate enantiomeric excess.
Abstract: The asymmetric oxidation of sulfides to sulfoxides is realised with layered double hydroxides (LDH)-supported OsO4 catalyst using N-methyl morpholine N-oxide as co-oxidant and (DHQD)2PHAL (hydroquinidine 1,4-phthalazinediyl diether) as a chiral ligand in good yields albeit moderate enantiomeric excess (e.e's).

24 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202385
2022177
202191
2020135
2019129
2018143