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Morpholine

About: Morpholine is a research topic. Over the lifetime, 5411 publications have been published within this topic receiving 51063 citations. The topic is also known as: diethylene imidoxide & diethylene oximide.


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Journal ArticleDOI
TL;DR: In this paper, morpholine was found to give slow and incomplete Fmoc removal resulting in substantial byproduct formation in solid phase synthesis of an O-linked HIV-related glycopeptide.

22 citations

Journal ArticleDOI
TL;DR: A series of N-morpholine or N,N-diethyl, N′-substituted benzoyl thioureas (R = Cl, Br, OMe or NO 2 in ortho, meta or para position) have been synthesized by condensation of morpholine or diethylamine with substituted benoyl isothiocyanates as mentioned in this paper.

22 citations

Journal ArticleDOI
TL;DR: In this paper, the stability of Fe(III with two buffer families, tris(hydroxymethyl)aminomethane (TRIS), N-[tris[tris]-methyl]-2-aminoethanesulfonic acid (TES), TAPS, and N-tris-methyl]-3amino-2-hydroxypropanesulfonic acids (TAPSO), were studied by potentiometric measurements.
Abstract: The complexation equilibria of Fe(III) with two buffer families, which are ubiquitous in biological system studies, were studied by potentiometric measurements at a constant ionic strength of I = 0.1 mol·dm−3 NaNO3 in aqueous solutions at 298.15 K. The members of TRIS family are tris(hydroxymethyl)aminomethane (TRIS), N-[tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid (TES), N-[tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid (TAPS), N-[tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid (TAPSO), and N-tris(hydroxymethyl)methyl-4-aminobutanesulfonic acid (TABS) buffers. The members of morpholine family are 4-morpholineethanesulfonic acid (MES), 4-morpholinepropanesulfonic acid (MOPS), 3-morpholino-2-hydroxypropanesulfonic acid (MOPSO), and 4-(N-morpholino) butanesulfonic acid (MOBS) buffers. The overall stability constants were determined from pH-metric data using the least-squares curve-fitting program HYPERQUAD 2008. Based on the best-fit results, the species formed at equilibrium are ML, ML2, ML2H−1, and ML3 in the systems with TRIS family buffers. The complex species ML, ML2, ML2H−1, and MLH−1 are formed in the MOPSO-containing system, while ML, ML2, and ML2H−1 are formed in the systems with MES, MOPS, and MOBS. The stabilities of the complexes fall in the order TABS > TRIS > TAPS > TAPSO > TES and MOBS > MOPS > MOPSO > MES for the TRIS family and morpholine families, respectively.

22 citations

Journal ArticleDOI
TL;DR: Aqueous solutions of the morpholine salt, at concentrations equivalent to 400 mg of cholesterol per deciliter, have been evaluated as aqueous cholesterol standards and compared to alcoholic cholesterol solutions in analyses for cholesterol in serum, as performed by two analytical reference procedures.
Abstract: We synthesized some inorganic and organic salts of cholesteryl hemisuccinate. Aqueous solutions of the morpholine salt, at concentrations equivalent to 400 mg of cholesterol per deciliter, have been evaluated as aqueous cholesterol standards and compared to alcoholic cholesterol solutions in analyses for cholesterol in serum, as performed by two analytical reference procedures. No significant differences were found. The usefulness of solutions of this salt as additives for serum controls or recovery studies has been also demonstrated.

22 citations

Journal ArticleDOI
TL;DR: Two new methods were developed for the analysis of aliphatic and alicyclic amines in water samples after derivatization and liquid-liquid-extraction and applications to German rivers and sewage plants show that both new methods produce corresponding results.
Abstract: Two new methods were developed for the analysis of aliphatic (n-propylamine, pentylamine, hexylamine, heptylamine, octylamine) and alicyclic (pyrrolidine, morpholine, piperidine, piperazine) amines in water samples after derivatization and liquid-liquid-extraction. The carbamate-derivatives formed were determined by GC/MS (trichloroethyl carbamates) as well as by HPLC/fluorescence detection (9-fluorenylmethyl carbamates) in a concentration range between 0.05 and 1.0 μg/l suitable for drinking water analysis. Applications to German rivers and sewage plants show that both new methods produce corresponding results in analysing aliphatic and alicyclic amines in surface waters as well as in waste water samples.

22 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202385
2022177
202191
2020135
2019129
2018143