Topic
Morpholine
About: Morpholine is a research topic. Over the lifetime, 5411 publications have been published within this topic receiving 51063 citations. The topic is also known as: diethylene imidoxide & diethylene oximide.
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TL;DR: In this article, the preparation of morpholine complexes of nickel(II), copper(II) and zinc(II)-sulphates is described, and possible structures for these complexes in the solid state are discussed.
36 citations
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TL;DR: In this article, the densities and volumetric specific heats of p-dioxane, tetrahydropyran, morpholine, piperidine, and piperazine were measured in water at 25 °C with a flow densimeter and a flow microcalorimeter.
Abstract: The densities and volumetric specific heats of p-dioxane, tetrahydropyran, morpholine, piperidine, and piperazine were measured in water at 25 °C with a flow densimeter and a flow microcalorimeter. The same properties were also determined for LiCl, NaCl, Me4NBr, and Bu4NBr at 0.1 m in dioxane–water, morpholine–water, and piperidine–water mixtures. The derived apparent molal volumes and heat capacities of the nonelectrolytes in water and the transfer functions of the electrolytes from water to the mixed solvent suggest that all the present cyclic amines and ethers are hydrophobic; the overall structural influence is very small with dioxane and large with piperidine.
36 citations
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TL;DR: In this article, the preparation of morpholine complexes of manganese (II), cobalt, copper, zinc, and cadmium (II) halides is described.
35 citations
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TL;DR: The present study successfully demonstrated the use of azaspiro substructure in the medicinal chemistry of antibacterial and antitubercular agents.
35 citations
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TL;DR: The obtained compounds were easily transformed into the bi- and tricyclic analogues of piperidine, morpholine, piperazine, and GABA, which are advanced building blocks for drug discovery.
Abstract: A one-step synthesis of functionalized 3-azabicyclo[3.2.0]heptanes by [2+2]-photochemical intermolecular cycloaddition of N-benzylmaleimide to alkenes was elaborated. The obtained compounds were easily transformed into the bi- and tricyclic analogues of piperidine, morpholine, piperazine, and GABA, which are advanced building blocks for drug discovery.
35 citations