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Topic

Multiple drug resistance

About: Multiple drug resistance is a research topic. Over the lifetime, 10710 publications have been published within this topic receiving 380396 citations. The topic is also known as: MDR & multidrug resistance.


Papers
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Journal ArticleDOI
07 Nov 1986-Cell
TL;DR: Results are consistent with a function for P-glycoprotein as an energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

1,914 citations

Journal ArticleDOI
TL;DR: 3 case histories-one involving Escherichia coli resistance to third-generation cephalosporins, another focusing on the emergence of vancomycin-resistant Staphylococcus aureus, and a third detailing multidrug resistance in Pseudomonas aeruginosa--are reviewed to illustrate the varied ways in which resistant bacteria develop.

1,697 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20231,056
20221,761
2021777
2020776
2019690
2018599