Topic
Multiple kernel learning
About: Multiple kernel learning is a research topic. Over the lifetime, 1630 publications have been published within this topic receiving 56082 citations.
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TL;DR: A multi-modal affective data analysis framework is proposed to extract user opinion and emotions from video content and outperforms the state-of-the-art model in multimodal sentiment analysis research with a margin of 10–13% and 3–5% accuracy on polarity detection and emotion recognition, respectively.
165 citations
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TL;DR: KronRLS-MKL, which models the drug-target interaction problem as a link prediction task on bipartite networks, allows the integration of multiple heterogeneous information sources for the identification of new interactions, and can also work with networks of arbitrary size.
Abstract: Drug-target networks are receiving a lot of attention in late years, given its relevance for pharmaceutical innovation and drug lead discovery. Different in silico approaches have been proposed for the identification of new drug-target interactions, many of which are based on kernel methods. Despite technical advances in the latest years, these methods are not able to cope with large drug-target interaction spaces and to integrate multiple sources of biological information. We propose KronRLS-MKL, which models the drug-target interaction problem as a link prediction task on bipartite networks. This method allows the integration of multiple heterogeneous information sources for the identification of new interactions, and can also work with networks of arbitrary size. Moreover, it automatically selects the more relevant kernels by returning weights indicating their importance in the drug-target prediction at hand. Empirical analysis on four data sets using twenty distinct kernels indicates that our method has higher or comparable predictive performance than 18 competing methods in all prediction tasks. Moreover, the predicted weights reflect the predictive quality of each kernel on exhaustive pairwise experiments, which indicates the success of the method to automatically reveal relevant biological sources. Our analysis show that the proposed data integration strategy is able to improve the quality of the predicted interactions, and can speed up the identification of new drug-target interactions as well as identify relevant information for the task. The source code and data sets are available at www.cin.ufpe.br/~acan/kronrlsmkl/
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163 citations
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TL;DR: A unified deep adaptation framework for jointly learning transferable representation and classifier to enable scalable domain adaptation, by taking the advantages of both deep learning and optimal two-sample matching is proposed.
Abstract: Domain adaptation generalizes a learning model across source domain and target domain that are sampled from different distributions. It is widely applied to cross-domain data mining for reusing labeled information and mitigating labeling consumption. Recent studies reveal that deep neural networks can learn abstract feature representation, which can reduce, but not remove, the cross-domain discrepancy. To enhance the invariance of deep representation and make it more transferable across domains, we propose a unified deep adaptation framework for jointly learning transferable representation and classifier to enable scalable domain adaptation, by taking the advantages of both deep learning and optimal two-sample matching. The framework constitutes two inter-dependent paradigms, unsupervised pre-training for effective training of deep models using deep denoising autoencoders, and supervised fine-tuning for effective exploitation of discriminative information using deep neural networks, both learned by embedding the deep representations to reproducing kernel Hilbert spaces (RKHSs) and optimally matching different domain distributions. To enable scalable learning, we develop a linear-time algorithm using unbiased estimate that scales linearly to large samples. Extensive empirical results show that the proposed framework significantly outperforms state of the art methods on diverse adaptation tasks: sentiment polarity prediction, email spam filtering, newsgroup content categorization, and visual object recognition.
161 citations
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TL;DR: A general learning framework, termed multiple kernel extreme learning machines (MK-ELM), to address the lack of a general framework for ELM to integrate multiple heterogeneous data sources for classification and can achieve comparable or even better classification performance than state-of-the-art MKL algorithms, while incurring much less computational cost.
160 citations
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TL;DR: It is shown empirically that the advantage of using the method proposed in this paper is even clearer when noise features are added, and the proposed method has been compared with other baselines and three state-of-the-art MKL methods showing that the approach is often superior.
159 citations