Nanobiotechnology

About: Nanobiotechnology is a research topic. Over the lifetime, 796 publications have been published within this topic receiving 46309 citations. The topic is also known as: bionanotechnology & nanobiology.

Nanobiotechnology-Based Anti-aging Products

Abstract: Nanobiotechnology is one of the fast-growing domains in the personal care sector and has played a major role in the arena of developing anti-aging products. The anti-aging products offered based on nanobiotechnology has a significant increase in their bioavailability levels with diverse and prolonged therapeutic effects. A large number of nano-based topical cures for anti-aging have become widespread. The present chapter figures out the therapeutic benefits and the potential side effects of various nano-biotechnology-based anti-aging products commercially available in the market.

Bacterial Synthesis and Applications of Nanoparticles

Abstract: Nanoparticles synthesis is the real division in the area of relevant Nanotechnology and Nanoscience. As of late, the merging amongst nanotechnology and science has made the new field of Nanobiotechnology that joins the utilization of natural elements, for example, algae, microscopic organisms, parasites, infections, yeasts and plants in various biophysical and biochemical procedures. The natural combination forms have a critical prospective to support nanoparticles generation without the utilization of brutal, harmful and costly chemicals usually utilized as a part of ordinary physical and substance forms. Combination of nanoparticles (NPs) utilizing microscopic organisms has risen as quickly creating research range in nanotechnology over the globe. The procedures of NPs combination result with required shapes and controlled sizes, quick and clean. These days, a variety of nanoparticles with very much characterized synthetic organization, size and morphology have been combined by utilizing distinctive microorganisms and their applications in numerous mechanical fields have been investigated. The uses of these biosynthesized nanoparticles in a wide range of potential zones are exhibited including focused on targeted drug passage, malignancy treatment and DNA investigation, biosensors and magnetic resonance imaging (MRI). The consumption of microorganisms for nanoparticles synthesis is a genuinely unique range of examination with extensive prospective for more improvement.

Bio-nano interfacial interactions for drug delivery systems

Abstract: Nanomaterials have shown interesting interactions with biological systems, which lead to the development of a newer avenue of research, namely bionanotechnology. The unique attributes of nanomaterials such as small size, large surface area, and tunable surface functionalities could render solutions associated with the modes of drug administration, target-specific delivery, and efficient interaction with biological systems. Drug delivery systems often confront issues such as side effects, inefficiency, and damage to nontarget tissues. Thus, targeted drug delivery is an exciting achievement of bionanotechnology. The size, dimension, and aspect ratio directly impacts the overall performance of a nanomaterial. Zero-dimensional colloidal nanoparticles to two-dimensional nanosheets have been investigated extensively in this regard. This chapter encompasses the important aspects of nanomaterials useful for designing drug delivery systems. Furthermore, this chapter demonstrates the mechanism and toxicity aspects of nanotechnology-based drug delivery systems. Commercial viability of such systems has also been analyzed herein in biocompatibility and efficiency at bio-nano interface.

[DNA complexes, formed on aqueous phase surfaces: new planar polymeric and composite nanostructures].

Abstract: The formation of DNA complexes with Langmuir monolayers of the cationic lipid octadecylamine (ODA) and the new amphiphilic polycation poly-4-vinylpyridine with 16% of cetylpyridinium groups (PVP-16) on the surface of an aqueous solution of native DNA of low ionic strength was studied. Topographic images of Langmuir-Blodgett films of DNA/ODA and DNA/PVP-16 complexes applied to micaceous substrates were investigated by the method of atomic force microscopy. It was found that films of the amphiphilic polycation have an ordered planar polycrystalline structure. The morphology of planar DNA complexes with the amphiphilic cation substantially depended on the incubation time and the phase state of the monolayer on the surface of the aqueous DNA solution. Complex structures and individual DNA molecules were observed on the surface of the amphiphilic monolayer. Along with quasi-linear individual bound DNA molecules, characteristic extended net-like structures and quasi-circular toroidal condensed conformations of planar DNA complexes were detected. Mono- and multilayer films of DNA/PVP-16 complexes were used as templates and nanoreactors for the synthesis of inorganic nanostructures via the binding of metal cations from the solution and subsequent generation of the inorganic phase. As a result, ultrathin polymeric composite films with integrated DNA building blocks and quasi-linear arrays of inorganic semiconductor (CdS) and iron oxide nanoparticles and nanowires were obtained. The nanostructures obtained were characterized by scanning probe microscopy and transmission electron microscopy techniques. The methods developed are promising for investigating the mechanisms of structural organization and transformation in DNA and polyelectrolyte complexes at the gas-liquid interface and for the design of new extremely thin highly ordered planar polymeric and composite materials, films, and coatings with controlled ultrastructure for applications in nanoelectronics and nanobiotechnology.