Topic
Nanobiotechnology
About: Nanobiotechnology is a research topic. Over the lifetime, 796 publications have been published within this topic receiving 46309 citations. The topic is also known as: bionanotechnology & nanobiology.
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TL;DR: This work has shown that double-stranded DNA or protein chains that are modified with metallic nanoclusters act as templates for the synthesis of metallic nanowires, which are used as building blocks to assemble nano-devices such as a transistor or a nanotransporter.
151 citations
01 Jan 2005
TL;DR: In this article, the authors propose a method for measuring the performance of a single node in a set of images.ING and INDEXING, e.g., this article.
Abstract: ING AND INDEXING
147 citations
TL;DR: This work has shown that solid-binding peptides show selectivity and bind with high affinity to the surfaces of a diverse range of solid materials, and have the ability to mediate the synthesis and construction of nanoparticles and complex nanostructures.
144 citations
TL;DR: The ability to incorporate drugs into nanosystems displays a new paradigm in pharmacotherapy that could be used for cell-targeted drug delivery and nanoparticle-based "molecular" imaging displays a field in which this new technology has set the stage for an evolutionary leap in diagnostic imaging.
Abstract: Nanoparticles are at the leading edge of the rapidly developing field of material science in nanotechnology with many potential applications in clinical medicine and research. Due to their unique size-dependent properties nanoparticles offer the possibility to develop both new therapeutic and diagnostic tools. The ability to incorporate drugs into nanosystems displays a new paradigm in pharmacotherapy that could be used for cell-targeted drug delivery. Nontargeted nanosystems such as nanocarriers that are coated with polymers or albumin and solid lipid particles have been used to transport a large number of compounds. However, nowadays drugs can be coupled to nanocarriers that are specific for cells and/or organs. Thus, drugs that are either trapped within the carriers or deposited in subsurface oil layers could be specifically delivered to organs, tumors and cells. These strategies can be used to concentrate drugs in selected target tissues thus minimizing systemic side effects and toxicity. In addition to these therapeutic options, nanoparticle-based "molecular" imaging displays a field in which this new technology has set the stage for an evolutionary leap in diagnostic imaging. Based on the recent progress in nanobiotechnology, nanoparticles have the potential to become useful tools as therapeutic and diagnostic tools in the near future.
139 citations
TL;DR: The optical and chemical properties of gold nanoparticles are described, and a number of specific applications within bionanotechnology are reviewed.
Abstract: Gold nanoparticles have unique optical and chemical properties that make them ideally suited for a number of applications in bionanotechnology, including optical probes, targeted drug delivery, and programmed materials synthesis. The recurring theme is the versatility of gold nanoparticles and how this versatility can be exploited to adapt gold nanoparticles to fit into different chemical environments—from aqueous suspensions to the hostile conditions of a cell culture or the human bloodstream. Herein, the optical and chemical properties of gold nanoparticles are described, and a number of specific applications within bionanotechnology are reviewed.
138 citations