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Nanodot
About: Nanodot is a research topic. Over the lifetime, 3173 publications have been published within this topic receiving 70767 citations.
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TL;DR: This Review summarize recent advances in the synthesis and characterization of C-dots and speculate on their future and discuss potential developments for their use in energy conversion/storage, bioimaging, drug delivery, sensors, diagnostics, and composites.
Abstract: Similar to its popular older cousins the fullerene, the carbon nanotube, and graphene, the latest form of nanocarbon, the carbon nanodot, is inspiring intensive research efforts in its own right. These surface-passivated carbonaceous quantum dots, so-called C-dots, combine several favorable attributes of traditional semiconductor-based quantum dots (namely, size- and wavelength-dependent luminescence emission, resistance to photobleaching, ease of bioconjugation) without incurring the burden of intrinsic toxicity or elemental scarcity and without the need for stringent, intricate, tedious, costly, or inefficient preparation steps. C-dots can be produced inexpensively and on a large scale (frequently using a one-step pathway and potentially from biomass waste-derived sources) by many approaches, ranging from simple candle burning to in situ dehydration reactions to laser ablation methods. In this Review, we summarize recent advances in the synthesis and characterization of C-dots. We also speculate on their future and discuss potential developments for their use in energy conversion/storage, bioimaging, drug delivery, sensors, diagnostics, and composites.
3,991 citations
1,768 citations
TL;DR: It is proposed that the range between 58-73 nm is a universal length scale for integrin clustering and activation, since these properties are shared by a variety of cultured cells.
Abstract: To study the function behind the molecular arrangement of single integrins in cell adhesion, we designed a hexagonally close-packed rigid template of cell-adhesive gold nanodots coated with cyclic RGDfK peptide by using block-copolymer micelle nanolithography. The diameter of the adhesive dots is or = 73 nm between the adhesive dots results in limited cell attachment and spreading, and dramatically reduces the formation of focal adhesion and actin stress fibers. We attribute these cellular responses to restricted integrin clustering rather than insufficient number of ligand molecules in the cell-matrix interface since "micro-nanopatterned" substrates consisting of alternating fields with dense and no nanodots do support cell adhesion. We propose that the range between 58-73 nm is a universal length scale for integrin clustering and activation, since these properties are shared by a variety of cultured cells.
1,146 citations
TL;DR: Carbon nanodots (C-dots) are fascinating carbon material that are attracting increasing interest because they possess distinct benefits, such as chemical inertness, a lack of opticalblinking, low photobleaching, low cytotoxicity, and excellent biocompatibility.
Abstract: Carbon nanodots (C-dots) are fascinating carbon materialsthat are attracting increasing interest because they possessdistinct benefits, such as chemical inertness, a lack of opticalblinking, low photobleaching, low cytotoxicity, and excellentbiocompatibility, compared with organic dyes and othersemiconductor nanodots with heavy metal cores.
1,096 citations
TL;DR: Highly fluorescent, water-soluble, few-atom Au quantum dots have been created that behave as multielectron artificial atoms with discrete, size-tunable electronic transitions throughout the visible and near IR.
Abstract: Highly fluorescent, water-soluble, few-atom Au quantum dots have been created that behave as multielectron artificial atoms with discrete, size-tunable electronic transitions throughout the visible and near IR. Correlation of nanodot sizes with emission energies fits the simple relation, ${E}_{\mathrm{F}\mathrm{e}\mathrm{r}\mathrm{m}\mathrm{i}}/{N}^{1/3}$, predicted by the jellium model. Providing the ``missing link'' between atomic and nanoparticle behavior in noble metals, these emissive, water-soluble Au nanoclusters open new opportunities for biological labels, energy transfer pairs, and light emitting sources in nanoscale optoelectronics.
1,001 citations