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Nanomedicine
About: Nanomedicine is a research topic. Over the lifetime, 4287 publications have been published within this topic receiving 200647 citations.
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TL;DR: This chapter serves as an introduction to the volume, giving a broad overview of applications of nan technology to medicine, and describes some of the beneficial aspects of nanotechnology-based drug delivery.
Abstract: Nanotechnology offers many potential benefits to medical research by making pharmaceuticals more efficacious and by decreasing their adverse side-effects Preclinical characterization of nanoparticles intended for medical applications is complicated--due to the variety of materials used, their unique surface properties and multifunctional nature This chapter serves as an introduction to the volume, giving a broad overview of applications of nanotechnology to medicine, and describes some of the beneficial aspects of nanotechnology-based drug delivery We define nanotechnology and provide brief descriptions of the major classes of nanomaterials used for medical applications The following two chapters discuss scientific and regulatory hurdles involved in the use of nanotechnology in medicine The remaining bulk of the volume provides the reader with protocols that have been tested against clinically relevant nanoparticles and describes some of the nuances of nanoparticle types and necessary controls
79 citations
TL;DR: The views of the board of the Nanomedicine and Nanoscale Delivery Focus Group of the Controlled Release Society regarding the decision of the United States National Cancer Institute in halting funding for the Centers of Cancer Nanotechnology Excellence (CCNEs) are conveyed.
Abstract: This commentary article conveys the views of the board of the Nanomedicine and Nanoscale Delivery Focus Group of the Controlled Release Society regarding the decision of the United States National Cancer Institute (NCI) in halting funding for the Centers of Cancer Nanotechnology Excellence (CCNEs), and the subsequent editorial articles that broadened this discussion. Graphical abstract.
78 citations
TL;DR: It was found that the presence of serum proteins is an absolute requirement for the uptake of folic acid-functionalized iron oxide nanoparticles, and the described strategy for receptor-mediated uptake of nanoparticles with pre-defined surface chemistry may enable a better targeting of nanoparticle for additional therapeutic and imaging applications.
78 citations
TL;DR: An in-depth overview of the recent advances in polymer nanomaterials for photothermal therapy is offered, describing the features of three different types of polymer-based nanommaterials and highlighting the relevant benefits.
78 citations
TL;DR: The basic rationale for developing bioresponsive cancer nanomedicine by exploiting the pathophysiological environment around the tumor, typically the pH, reactive oxygen species (ROS), and redox-responsive supramolecular motifs based on synthetic amphiphilic polymers are discussed.
Abstract: ConspectusUnderstanding the interactions between nanomaterials and biological systems plays a pivotal role in enhancing the efficacy of nanomedicine and advancing the disease diagnosis. The nanopar...
78 citations