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Showing papers on "Nanoparticle published in 1988"


Journal ArticleDOI
TL;DR: The optimal conditions for the synthesis of PGNP were found to be: 7% glutaraldehyde, 2.5% dextran, pH 12, 70% oxygen, and a stirring rate of 1080 rpm, and the values of the dependent variables adequately resembled those predicted by the model.

26 citations


Journal ArticleDOI
TL;DR: The magno-responsive indomethacin nanoparticles were successfully prepared and the drug was embedded in the nanoparticles by the emulsion polymerization technique.
Abstract: Nanoparticles of polymethylmethacrylate were prepared by the emulsion polymerization technique. The drug was embedded in the nanoparticles. The controlled growth of ferric hydroxide particles in the presence of non-ionic surfactant was effected to obtain nano-size particles and these were subsequently heated to obtain ferroso-ferric oxide (magnetite). The effect of various parameters, i.e. monomer concentration and magnetite concentration, as well as the stirring rate were studied to characterize the particle size and its distribution. Similarly, the factors which affect the total drug payload were assessed. The magno-responsive indomethacin nanoparticles were successfully prepared.

22 citations