Topic
Nerve root
About: Nerve root is a research topic. Over the lifetime, 5188 publications have been published within this topic receiving 123478 citations.
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TL;DR: The origin, termination, and length of axonal growth after focal central nervous system injury was examined in adult rats by means of a new experimental model and the regenerative potential of these central neurons seems to be expressed when the central nervous System glial environment is changed to that of the peripheral nervous system.
Abstract: The origin, termination, and length of axonal growth after focal central nervous system injury was examined in adult rats by means of a new experimental model. When peripheral nerve segments were used as "bridges" between the medulla and spinal cord, axons from neurons at both these levels grew approximately 30 millimeters. The regenerative potential of these central neurons seems to be expressed when the central nervous system glial environment is changed to that of the peripheral nervous system.
1,665 citations
1,187 citations
TL;DR: Electrophysiological evidence of associated neural lesions in the neck of patients with carpal-tunnel syndromes or lesions of the ulnar nerve at the elbow is thought to be fortuitous, but rather the result of serial constraints of axoplasmic flow in nerve fibres.
882 citations
TL;DR: It is suggested that a radical exposure of the nerve root should be undertaken in all patients in whom the intervertebral disc fails to reveal pathological changes of sufficient degree to account for the nerve-root compression or tautness demonstrated.
Abstract: In 842 patients, with the clinical diagnosis of root compression due to a disc herniation, laminectomy failed to reveal any lesion of the intervertebral disc in sixty-eight patients. In nine, the source of the root compression was found to be foraminal migration of a sequestrated portion of the intervertebral disc; in twelve, pedicular kinking; in nineteen, articular-process impingement; in eight, segmental spinal stenosis; and in two, a lateral disc protrusion.
In eighteen explorations, performed early in the series, no cause could be found for the root compression, and it is suggested that the lack of findings in these cases was due to inadequate exploration of the nerve root.
The series analyzed is too small to make any dogmatic statements. However, a plea is entered for a careful appraisal of the level of root involvement preoperatively, using all ancillary methods available—myelography, discography root-sleeve injection, electromyography, diagnostic differential epidural injections—in patients without objective signs of the site of root involvement. Armed with such evidence, it is suggested that a radical exposure of the nerve root should be undertaken in all patients in whom the intervertebral disc fails to reveal pathological changes of sufficient degree to account for the nerve-root compression or tautness demonstrated.
876 citations
TL;DR: No signs of excitatory on inhibitory interaction were detected between volleys in one group of nerve fibers and the activity in other groups of fibers in the neuroma, suggesting that alpha blocking agents might be useful to test if the sympathetic system is involved in particular pains.
701 citations