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Nigella damascena

About: Nigella damascena is a(n) research topic. Over the lifetime, 121 publication(s) have been published within this topic receiving 1390 citation(s). The topic is also known as: love-in-a-mist & Devil-in-a-bush.


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Journal ArticleDOI
TL;DR: The two species had positive agronomic traits, such as short growing cycle, low seed shattering and low susceptibility to diseases, and different possible options for direct utilisation or industrial processing, may determine an interest in further considering the two species as potential new multi-purpose crops.
Abstract: Nigella sativa and Nigella damascena are two annual species of the family Ranunculaceae, investigated recently for the oil, essential oil and other biologically active constituents of their seeds. They are presently used in traditional medicine and for culinary preparations in many countries, as ornamentals, and are also considered for their abundant nectar secretion. One accession of N. sativa and two of N. damascena were compared on three spring sowing dates in northern Italy. Seed yield, yield components, essential oil content and composition were evaluated. Oil content was also measured in N. sativa. Total and seed biomass decreased with delayed sowing, because of a reduction in both seed number per plant and mean seed weight. Seed number per plant was the more important yield component for both species. Actual seed yield was lower for N. sativa, whereas yield potential seemed to be similar for the two species. The main constraint to yield potential of N. sativa seemed to be connected to its short vegetative phase, with consequently low number of seeds per unit area. The essential oil composition differed markedly in the two species. Monoterpenes were dominant in N. sativa, with p-cymene and thymol as the main components. The amount of pharmacologically active thymoquinone was lower than reported in the literature. N. damascena essential oil was almost completely composed of sesquiterpenes. Essential oil composition was very stable in N. damascena, but markedly affected by sowing date in N. sativa. Oil yield of N. sativa decreased with delayed sowing. As a whole, the two species had positive agronomic traits, such as short growing cycle, low seed shattering and low susceptibility to diseases. This, together with different possible options for direct utilisation or industrial processing, may determine an interest in further considering the two species as potential new multi-purpose crops.

161 citations

Journal ArticleDOI
TL;DR: The technique used does not stain centromeres in other plant species investigated, a fact which shows that the centromres of Nigella are in some way different, and the implications of this observation in relation to centromere polymorphism are discussed.
Abstract: The centromere regions of each chromosome in the complement of Nigella damascena (2n equals 2x equals 12) stain differentially with Giemsa at interphase and throughout all the principal stages of mitosis and meiosis. Each centromere is seen to consist of a pair of sister half-centromeres which appear as 2 differentially stained dots. The appearance and behaviour of these dots indicates that they are kinetochores. The technique used does not stain centromeres in other plant species investigated, a fact which shows that the centromeres of Nigella are in some way different. The implications of this observation in relation to centromere polymorphism are discussed.

83 citations

Journal ArticleDOI
TL;DR: It is interpreted that the observed differences between Vicia and Nigella are due to the presence and absence of heterochromatin in their chromosome complements respectively.
Abstract: The chromosome breaking effect of mitomycin C, methyl methanesulfonate, maleic hydrazide, 8-ethoxycaffeine and gamma rays on the primary root meristematic cells of Nigella damascena was studied. All the agents tested except 8-ethoxycaffeine, produced relatively fewer aberrations, when compared to Vicia faba cells, though both the species have nearly similar total chromosomal length. Test for the presence of heterochromatin in Nigella gave negative results and it is interpreted that the observed differences between Vicia and Nigella are due to the presence and absence of heterochromatin in their chromosome complements respectively. The role of heterochromatin in the production of chromosome aberrations and its significance in evolution are briefly discussed.

78 citations

Journal ArticleDOI
TL;DR: The antioxidant potential of the two species was tested through several electron transfer assays, which indicated, excepting for the FRAP assay, N. damascena as exhibiting a higher free radical scavenging activity.
Abstract: This study was performed to evaluate the phenolic profile, antioxidant and diuretic effects of black cumin and lady-in-a-mist seeds. In the phenolic profile, differences between the two species are significant. Qualitative and quantitative analyses of the phenolic compounds were performed using a HPLC-UV/MS method. Hyperoside was the only identified flavonoid glycoside (1.08 ± 0.01 μg∙g−1 dw plant material), in the N. damascena extract. Regarding the flavonol profile, kaempferol was identified before the hydrolysis, only in the N. sativa extract (6.06 ± 0.02 μg∙g−1 dw plant material) and quercetin only in N. damascena seeds (14.35 ± 0.02 μg∙g−1 dw plant material). The antioxidant potential of the two species was tested through several electron transfer assays, which indicated, excepting for the FRAP assay, N. damascena as exhibiting a higher free radical scavenging activity. The diuretic activity of the two extracts was tested using a rat-experimental model on acute diuresis. Administration of the ethanolic extract of N. sativa (100 mg∙kg−1) resulted in a significant increase in urine volume, although less than found with the reference drug; in addition N. damascena extract did not present a diuretic effect. In reference to the elimination of Na+, K+ and uric acid, the black cumin extract exhibited a higher natriuretic than kaluretic effect and a similar uricosuric effect with control and N. damascena. For N. damascena, the Na+/K+ ratio was sub unitary, but not due to an increasing of the kaluretic effect, but mostly to a decrease of Na+ excretion.

54 citations

Journal ArticleDOI
TL;DR: N. arvensis chloroform extract was the most potent among all species tested, inhibiting Gram-positive bacterial and yeast strains with minimum inhibitory concentration values ranging from 0.25 to 1 mg/mL.
Abstract: Seed extracts from six species of the genus Nigella (Family Ranunculaceae)-Nigella arvensis, Nigella damascena, Nigella hispanica, Nigella nigellastrum, Nigella orientalis, and Nigella sativa-obtained by successive extraction with n-hexane, chloroform, and methanol, were tested for their antimicrobial activity against 10 strains of pathogenic bacteria and yeast using the microdilution method as well as for anti-inflammatory properties by in vitro cyclooxygenase (COX)-1 and COX-2 assay. Chemical characterization of active extracts was carried out including free and fixed fatty acid analysis. Comparison of antimicrobial activity showed that N. arvensis chloroform extract was the most potent among all species tested, inhibiting Gram-positive bacterial and yeast strains with minimum inhibitory concentration (MIC) values ranging from 0.25 to 1 mg/mL. With the exception of selective inhibitory action of n-hexane extract of N. orientalis on growth of Bacteroides fragilis (MIC = 0.5 mg/mL), we observed no antimicrobial activity for other Nigella species. Anti-inflammatory screening revealed that N. sativa, N. orientalis, N. hispanica, N. arvensis n-hexane, and N. hispanica chloroform extracts had strong inhibitory activity (more than 80%) on COX-1 and N. orientalis, N. arvensis, and N. hispanica n-hexane extracts were most effective against COX-2, when the concentration of extracts was 100 microg/mL in both COX assays. In conclusion, N. arvensis, N. orientalis, and N. hispanica seeds, for the first time examined for antimicrobial and anti-inflammatory effects, revealed their significant activity in one or both assays.

41 citations

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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20214
20205
20194
20184
20173
20162