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Showing papers on "Nigella damascena published in 2014"


Journal ArticleDOI
TL;DR: The influence of supercritical fluid extraction (SFE) conditions on the yield and concentration of volatiles in the extract and the extraction kinetics were studied in this article, where β-Elemene, germacrene A and damascenine were extracted from lady-in-a-mist (Nigella damascena L.) seeds with supercritical carbon dioxide at 10-30-MPa and 40-60-°C.
Abstract: β-Elemene, germacrene A and damascenine were extracted from lady-in-a-mist (Nigella damascena L.) seeds with supercritical carbon dioxide at 10–30 MPa and 40–60 °C. The influence of supercritical fluid extraction (SFE) conditions on the yield and concentration of volatiles in the extract and the extraction kinetics were studied. The extraction yields and the apparent solubility of volatile compounds increased with increasing density of CO2. The highest total yield was obtained at 30 MPa and 40 °C but the selectivity for volatiles was low under these conditions. With respect to both yield of volatiles and their concentration in extract, the best results were at 12 MPa and 40 °C, either with one separator or with additional separator maintained at 5 MPa and 25 °C. The yields of β-elemene, germacrene A and damascenine reached 0.72, 3.31 and 3.65 mg g−1 and their concentration in the extract was 2.62, 12.04 and 13.28 wt.%, respectively. Though the yields of germacrene A and damascenine were by about 20% higher using Soxhlet extraction with hexane than using SFE, their concentration in the extract where fatty oil prevailed was only 1.19 and 1.20 wt.%, respectively. Under the conditions of hydrodistillation, partial conversion of germacrene A to β-elemene occurred and its yield was higher than using the other methods but the composition of volatiles in the SFE extracts better corresponds to the original raw material.

10 citations


Patent
07 May 2014
TL;DR: Wang et al. as mentioned in this paper provided an eyebrow growth liquid, which is prepared from the following active ingredients: Isatis tinctoria leaf, Polygonum multiflorum root, Platycladus orientalis leaf and Nigella damascena seed, and preferably ethanol.
Abstract: The invention provides eyebrow growth liquid, which is prepared from the following active ingredients: Isatis tinctoria leaf, Polygonum multiflorum root, Platycladus orientalis leaf and Nigella damascena seed, and preferably ethanol. A preparation method of the eyebrow growth liquid includes the following steps: (1) weighing raw materials proportionally; (2) mixing Isatis tinctoria leaf, Polygonum multiflorum root, Platycladus orientalis leaf and Nigella damascena seed proportionally, adding 10-70 v/v% ethanol (8-15 times of the weight of the mixture), reflux-extracting, and concentrating to obtain ethanol extractive solution of Isatis tinctoria leaf, Polygonum multiflorum root, Platycladus orientalis leaf and Nigella damascena seed; and (3) adding additives into the ethanol extractive solution, and stirring to obtain the eyebrow growth liquid. The eyebrow growth liquid of the invention has good eyebrow growth effect, meets the needs of populations with rare eyebrow, eyebrow loss and eyebrow absence, and meets the pursuance of people for beauty and high quality of life. The eyebrow growth liquid is deep yellow liquid, and has unique herbal medicine fragrance, and good compliance.

1 citations


Patent
28 Aug 2014
TL;DR: In this paper, a melanocyte differentiation induction inhibitor consisting of Nigella damascena polysaccharides as an active ingredient was proposed. But it was only applied to melanocytes.
Abstract: PROBLEM TO BE SOLVED: To provide a melanocyte differentiation induction inhibitor having the activity to inhibit differentiation induction from a stem cell to a melanocyte.SOLUTION: A melanocyte differentiation induction inhibitor comprises Nigella damascena polysaccharides as an active ingredient.