Topic
Nigella damascena
About: Nigella damascena is a research topic. Over the lifetime, 121 publications have been published within this topic receiving 1390 citations. The topic is also known as: love-in-a-mist & Devil-in-a-bush.
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TL;DR: The structural determination of new compounds damasterpenes V–VIII is described with consideration of their absolute configurations and the antiviral activities against herpes simplex virus type-1 of the isolated compounds and their derivatives are evaluated.
Abstract: Nigella species are rich source of dolabellane diterpenes. During our study of Nigella species, new dolabellane diterpenes, damasterpenes V–VIII were isolated. The structural determination of new compounds damasterpenes V–VIII is described with consideration of their absolute configurations. The antiviral activities against herpes simplex virus type-1 of the isolated compounds and their derivatives are also evaluated. Damasterpene V (inhibition 35.0%) and 2-phenylacetyl 13-benzoyl damasterpenol (32.0%) showed significant antiviral activity at 10 μM.
11 citations
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TL;DR: Nigella damascena has 2n=12 chromosomes composed of five long metacentric chromosome pairs and a short telocentric chromosome pair and FISH using rDNA probes was applied on the chromosomes of this species.
Abstract: Nigella damascena has 2n=12 chromosomes composed of five long metacentric chromosome pairs and a short telocentric chromosome pair. FISH using rDNA probes was applied on the chromosomes of this species. 45S rDNA were located at the terminal region of three pairs of long metacentric chromosomes and a pair of short chromosomes. 5S rDNA appeared at the interstitial regions of the short arm of two long metacentric chromosomes.
11 citations
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TL;DR: A precise comparative schedule of floral development in the two floral morphs ofLove-in-a-mist (Nigella damascena) is described, providing further insight into the molecular control of the floral dimorphism in N. damascena and into the processes underlying the transition from a differentiated to an undifferentiated perianth.
11 citations
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01 Aug 1978TL;DR: The ovule primordium of Nigella damascena is three-zonate, and the nucellus of most ovules is crassinucellate, which correspond with those of the supposedly most original type of the angiospermous ovule.
Abstract: SUMMARY
The ovule primordium of Nigella damascena is three-zonate. The nucellus of most ovules is crassinucellate. The inner integument is of dermal origin, whereas the outer integument is initiated subdermally. These ovule characteristics correspond with those of the supposedly most original type of the angiospermous ovule. The ovule can be used as a base of comparison with unitegmic ranunculaceous ovules and with ovules showing a structure intermediate between bi- and unitegmy.
11 citations
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TL;DR: The influence of supercritical fluid extraction (SFE) conditions on the yield and concentration of volatiles in the extract and the extraction kinetics were studied in this article, where β-Elemene, germacrene A and damascenine were extracted from lady-in-a-mist (Nigella damascena L.) seeds with supercritical carbon dioxide at 10-30-MPa and 40-60-°C.
Abstract: β-Elemene, germacrene A and damascenine were extracted from lady-in-a-mist (Nigella damascena L.) seeds with supercritical carbon dioxide at 10–30 MPa and 40–60 °C. The influence of supercritical fluid extraction (SFE) conditions on the yield and concentration of volatiles in the extract and the extraction kinetics were studied. The extraction yields and the apparent solubility of volatile compounds increased with increasing density of CO2. The highest total yield was obtained at 30 MPa and 40 °C but the selectivity for volatiles was low under these conditions. With respect to both yield of volatiles and their concentration in extract, the best results were at 12 MPa and 40 °C, either with one separator or with additional separator maintained at 5 MPa and 25 °C. The yields of β-elemene, germacrene A and damascenine reached 0.72, 3.31 and 3.65 mg g−1 and their concentration in the extract was 2.62, 12.04 and 13.28 wt.%, respectively. Though the yields of germacrene A and damascenine were by about 20% higher using Soxhlet extraction with hexane than using SFE, their concentration in the extract where fatty oil prevailed was only 1.19 and 1.20 wt.%, respectively. Under the conditions of hydrodistillation, partial conversion of germacrene A to β-elemene occurred and its yield was higher than using the other methods but the composition of volatiles in the SFE extracts better corresponds to the original raw material.
10 citations