scispace - formally typeset
Search or ask a question
Topic

Nigella damascena

About: Nigella damascena is a research topic. Over the lifetime, 121 publications have been published within this topic receiving 1390 citations. The topic is also known as: love-in-a-mist & Devil-in-a-bush.


Papers
More filters
Journal Article
TL;DR: No significant differences were observed concerning glucose, cholesterol, bilirubine, aspartate transaminase (AST), alanine aminotransferase (ALT), urea, creatinine, total protein or albumin parameters in Nigella damascena in mice, and no histopathological alterations had been observed in the kidney and liver structures.
Abstract: Nigella damascena is an herbaceous annual plant used in Oriental herbal medicine for the treatment of catarrhal affections, amenorrhea and as a diuretic; powdered seeds are used as sternutatory. No systematic study of the potential toxicity of the plant has been described. This study aimed to determine the toxicity profile of methanolic seed extract from Nigella damascena in mice. In acute and sub-chronic toxicity study, a total of 42 adult male Swiss albino mice wereused. No mortality or abnormal behavior were observed in acute toxicity study at oral doses of 1, 2 and 5g/kg. In sub-chronic toxicity study when working at 100 and 400mg/kg respectively, no significant differences were observed concerning glucose, cholesterol, bilirubine, aspartate transaminase (AST), alanine aminotransferase (ALT), urea, creatinine, total protein or albumin parameters. In the same manner, no histopathological alterations had been observed in the kidney and liver structures.

6 citations

01 Jan 2013
TL;DR: A morphological and microscopic examination of N. sativa and N. damascena seeds showed for the first time that physical differences barely discernible on to the naked eye are readily identifiable using a 20-fold magnification.
Abstract: The seeds of Nigella sativa L. have been shown in both in-vitro and in-vivo to possess interesting pharmacological properties. These properties have been attributed to the volatile fraction, the principal component of which is thymoquinone. If clinical studies of N. sativa are to be envisaged it will be necessary to develop a means to ensure the homogeneity of different sources and to avoid confusion, notably with N. damascena the seeds of which closely resemble those of N. sativa. Gas chromatography coupled to mass spectrometry was used to analyse the volatile and fixed oil composition of different sources of N. sativa seeds. There was a substantial variation in the volatile fraction between the different sources, whereas the fixed oil composition remained relatively constant. In addition, the GC chromatograms of volatile fractions of N. sativa and N. damascena were remarkably different; the presence of the toxic compound, damascene was confirmed in N. damascena and thymoquinone was shown to be absent from this species of Nigella. A morphological and microscopic examination of N. sativa and N. damascena seeds showed for the first time that physical differences barely discernible on to the naked eye are readily identifiable using a 20-fold magnification.

6 citations

Journal ArticleDOI
TL;DR: A cytological investigation of the endosperms of Nigella damascena and N. sativa fixed at various intervals after pollination reveals that the nuclei in both taxa are uniform in size and shape, and the absence of higher polyploidy may presumably be correlated with the uniformity noticed in theendosperm nuclei of both entities.
Abstract: SUMMARY1. A cytological investigation of the endosperms of Nigella damascena and N. sativa fixed at various intervals after pollination reveals that the nuclei in both taxa are uniform in size and shape.2. The haploid chromosome number in the two species is the same i.e. n = 6.3. Although the normal cytological constitution of the endosperm in either case is triploid (3 n = 18), nuclei exhibiting aneuploid chromosome numbers do occur in small proportions.4. Cytological aberrations including dicentric bridges and tripolar anaphases are present.5. Polyploidy higher than 3 n is not recorded. This absence of higher polyploidy may presumably be correlated with the uniformity noticed in the endosperm nuclei of both the entities.

6 citations

Journal ArticleDOI
TL;DR: Cytomorphological studies including scanning electron microscopy of the seed surfaces and seed protein characterization have been performed to ascertain interrelationship between 2 species of Nigella (Ranunculaceae) namely, Nigella sativa L. sativa and Nigella damascena and the results obtained have been discussed.
Abstract: Cytomorphological studies including scanning electron microscopy of the seed surfaces and seed protein characterization have been performed to ascertain interrelationship between 2 species of Nigella (Ranunculaceae) namely, Nigella sativa L. (black cumin: spice of commerce) and Nigella damascena L. (love-in-a-mist: ornamental) and the results obtained have been discussed. Further, in this investigation it has also been noted that a line of N. damascena obtained from Royal Botanic Garden, Kew. London possessed unique ornamental phenotype and yielded good number of viable seeds per plant which were with high protein content.

6 citations


Network Information
Related Topics (5)
Cyanidin
1.6K papers, 77.8K citations
71% related
Iridoid Glucosides
604 papers, 12.2K citations
71% related
Pfaffia glomerata
131 papers, 1.7K citations
69% related
Helichrysum
352 papers, 7K citations
69% related
Centaurium erythraea
128 papers, 2.6K citations
69% related
Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20214
20205
20194
20184
20173
20162