Topic
Nitrite
About: Nitrite is a research topic. Over the lifetime, 15425 publications have been published within this topic receiving 484581 citations.
Papers published on a yearly basis
Papers
More filters
TL;DR: HyHyphomicrobrium spp was found as dominant organism in a two-sludge nitrifying-denitrifying wastewater treatment system with methanol as external carbon source as discussed by the authors.
155 citations
TL;DR: Nitrite levels in breath condensate were raised in stable patients with cystic fibrosis in contrast to exhaled NO, suggesting that nitrite levels may be a more useful measure of NO production and possibly airways inflammation in suppurative airways and that exhaled No may not reflect total NO production.
Abstract: BACKGROUND: Nitric oxide (NO) is released by activated macrophages, neutrophils, and stimulated bronchial epithelial cells. Exhaled NO has been shown to be increased in patients with asthma and has been put forward as a marker of airways inflammation. However, we have found that exhaled NO is not raised in patients with cystic fibrosis, even during infective pulmonary exacerbation. One reason for this may be that excess airway secretions may prevent diffusion of gaseous NO into the airway lumen. We hypothesised that exhaled NO may not reflect total NO production in chronically suppurative airways and investigated nitrite as another marker of NO production. METHODS: Breath condensate nitrite concentration and exhaled NO levels were measured in 21 clinically stable patients with cystic fibrosis of mean age 26 years and mean FEV1 57% and 12 healthy normal volunteers of mean age 31 years. Breath condensate was collected with a validated method which excluded saliva and nasal air contamination and nitrite levels were measured using the Griess reaction. Exhaled NO was measured using a sensitive chemiluminescence analyser (LR2000) at an exhalation rate of 250 ml/s. Fourteen patients with cystic fibrosis had circulating plasma leucocyte levels and differential analysis performed on the day of breath collection. RESULTS: Nitrite levels were significantly higher in patients with cystic fibrosis than in normal subjects (median 1.93 microM compared with 0.33 microM). This correlated positively with circulating plasma leucocytes and neutrophils (r = 0.6). In contrast, exhaled NO values were not significantly different from the normal range (median 3.8 ppb vs 4.4 ppb). There was no correlation between breath condensate nitrite and lung function and between breath condensate nitrite and exhaled NO. CONCLUSIONS: Nitrite levels in breath condensate were raised in stable patients with cystic fibrosis in contrast to exhaled NO. This suggests that nitrite levels may be a more useful measure of NO production and possibly airways inflammation in suppurative airways and that exhaled NO may not reflect total NO production.
155 citations
TL;DR: The enzymatic system involved in nitric oxide synthesis by murine macrophages consists of at least one inducible and two constitutive components.
155 citations
TL;DR: Six months after start-up, nitrite oxidisers showed increasing activities for the same specific free ammonia concentration, specially in the filter started in batch mode, which appeared to be a consequence of the capability of the nitrifying microorganisms to become acclimated to higher concentrations of free ammonia.
155 citations
TL;DR: In this paper, the minor and major mineral contents of 31 medicinal and aromatic plants collected from the south region of Turkey in 2004 year were established by inductively coupled plasma atomic emission spectrometry (ICP-AES).
154 citations