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Non-rapid eye movement sleep

About: Non-rapid eye movement sleep is a research topic. Over the lifetime, 8661 publications have been published within this topic receiving 389465 citations. The topic is also known as: NREM.


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Journal ArticleDOI
TL;DR: It is shown that subjective and objective measures of sleep vary according to lunar phase and thus may reflect circalunar rhythmicity in humans and is the first reliable evidence that a lunar rhythm can modulate sleep structure in humans when measured under the highly controlled conditions of a circadian laboratory study protocol without time cues.

123 citations

Journal ArticleDOI
TL;DR: In healthy young women, rapid eye movement sleep decreased, slow-wave sleep increased, sleep-onset latency decreased and late-night disturbance of sleep increased with increasing doses of alcohol.
Abstract: In healthy young women, rapid eye movement sleep decreased, slow-wave sleep increased, sleep-onset latency decreased and late-night disturbance of sleep increased with increasing doses of alcohol.

123 citations

Journal ArticleDOI
TL;DR: The serial awakening paradigm allowed us to collect a large and representative sample of conscious experiences across states of being and represents a time-efficient method for the study of sleep consciousness that may prove particularly advantageous when combined with techniques such as functional MRI and high-density EEG.
Abstract: Dreaming-a particular form of consciousness that occurs during sleep-undergoes major changes in the course of the night. We aimed to outline state-dependent features of consciousness using a paradigm with multiple serial awakenings/questionings that allowed for within as well as between subject comparisons. Seven healthy participants who spent 44 experimental study nights in the laboratory were awakened by a computerized sound at 15-30 min intervals, regardless of sleep stage, and questioned for the presence or absence of sleep consciousness. Recall without content ("I was experiencing something but do not remember what") was considered separately. Subjects had to indicate the content of the most recent conscious experience prior to the alarm sound and to estimate its duration and richness. We also assessed the degree of thinking and perceiving, self- and environment-relatedness and reflective consciousness of the experiences. Of the 778 questionings, 5% were performed during wakefulness, 2% in stage N1, 42% in N2, 33% in N3, and 17% in rapid eye movement (REM) sleep. Recall with content was reported in 34% of non-REM and in 77% of REM sleep awakenings. Sleep fragmentation inherent to the study design appeared to only minimally affect the recall of conscious experiences. Each stage displayed a unique combination of characteristic features of sleep consciousness. In conclusion, our serial awakening paradigm allowed us to collect a large and representative sample of conscious experiences across states of being. It represents a time-efficient method for the study of sleep consciousness that may prove particularly advantageous when combined with techniques such as functional MRI and high-density EEG.

123 citations

Journal ArticleDOI
TL;DR: During all sleep, spontaneous EDA occurred most frequently during stages 3 and 4 and least frequently during stage 1 (rapid eye movement [REM] and non-REM).
Abstract: Spontaneous electrodermal activity (EDA) (galvanic skin response [GSR] and skin potential response [SPR]) was recorded during daytime sleep and nighttime sleep. During all sleep, spontaneous EDA occurred most frequently during stages 3 and 4 (slow wave sleep) and least frequently during stage 1 (rapid eye movement [REM] and non-REM). This pattern was consistent over 3 nights of sleep. There was no relation between waking and sleeping spontaneous EDA. The spontaneous EDA during slow wave sleep significantly exceeded that during waking. During sleep, spontaneous SPRs often occurred without spontaneous GSRs.

123 citations

Journal ArticleDOI
01 Mar 1986-Sleep
TL;DR: It is argued that in pathophysiological terms narcolepsy may best be considered a disease of state boundary control.
Abstract: The main disabling symptom of narcolepsy-cataplexy is shown to be the unrelenting excessive daytime sleepiness (EDS) based upon controlled studies of socioeconomic effects and the poor response to treatment. Objective performance deficits mainly involve tests of ability to sustain performance on repetitive boring tasks and are reversible by improved alertness. Physiologically, EDS is seen to represent relatively slow waxing and waning of alertness rather than punctate microsleeps. Evidence is provided for complex cerebral evoked potentials (P300, contingent negative variation) being very sensitive EDS measures comparable to the multiple sleep latency test (MSLT). EDS appears to have qualitatively somewhat different forms mainly reflecting pressure for REM sleep (REM sleepiness) or pressure for NREM sleep (NREM sleepiness), which have different effects on cerebral evoked potentials as well as subjective and objective (MSLT) differences. It is argued that in pathophysiological terms narcolepsy may best be considered a disease of state boundary control.

123 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
2023229
2022453
2021353
2020283
2019315
2018221