Topic
Non-rapid eye movement sleep
About: Non-rapid eye movement sleep is a research topic. Over the lifetime, 8661 publications have been published within this topic receiving 389465 citations. The topic is also known as: NREM.
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TL;DR: It appears that reduced slow wave sleep may be related to a neurodevelopmental disorder related to the defect state in schizophrenia, and the pathophysiological significance of the defective REM rebound and the REM sleep abnormalities in schizophrenia remain uncertain.
105 citations
Journal Article•
TL;DR: It is suggested that GHB may serve as the prototype for a new class of hypnotic compounds derived from natural sources and capable of activating the neurological mechanisms of normal human sleep.
105 citations
TL;DR: Electroencephalographic sleep patterns were examined in unmedicated patients meeting DSM-III-R criteria for a current manic episode to suggest that mania is associated with marked disturbances of sleep continuity and REM measures.
Abstract: • Electroencephalographic (EEG) sleep patterns were examined in nine unmedicated patients meeting DSM-III-R criteria for a current manic episode (four men and five women) for two to four consecutive nights. Compared with age- and sex-matched normal control subjects, manic patients exhibited significantly decreased total recording period, decreased time spent asleep, increased time awake in the last two hours of recording, shortened rapid eye movement (REM) latency, increased REM activity, and increased REM density. These results suggest that mania is associated with marked disturbances of sleep continuity and REM measures. Sleep continuity and REM sleep abnormalities of a similar nature and degree have been reported in major depression and psychotic depression. Thus, it is possible that various forms of affective disorders and psychotic disorders have pathophysiologic mechanisms in common.
105 citations
Journal Article•
TL;DR: The results provided convincing support for a causal relationship between CCU sound levels and suppression of REM sleep and generalization to CCU patients is limited.
105 citations
TL;DR: The data confirm that social defeat stress accelerates the build up of sleep debt and support the notion thatSleep debt and subsequent NREM sleep intensity not only depend on the duration of prior wakefulness but also on what animals experience during that waking.
105 citations