Topic
Non-rapid eye movement sleep
About: Non-rapid eye movement sleep is a research topic. Over the lifetime, 8661 publications have been published within this topic receiving 389465 citations. The topic is also known as: NREM.
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TL;DR: Functional magnetic resonance imaging data is presented demonstrating a change in the representation of a motor memory after a night of sleep, which holds important implications for acquiring real-life skills and in clinical rehabilitation following brain trauma, such as stroke.
296 citations
TL;DR: A new clinical syndrome, sleep apnea associated with insomnia, has been characterized and an important clinical implication is that patients complaining only of insomnia may be suffering from this syndrome.
Abstract: A new clinical syndrome, sleep apnea associated with insomnia, has been characterized. Repeated episodes of apnea occur during sleep. Onset of respiration is associated with general arousal and often complete awakening, with a resultant loss of sleep. An important clinical implication is that patients complaining only of insomnia may be suffering from this syndrome.
296 citations
TL;DR: It is concluded that the data best support the idea of special periods of paradoxical sleep within the 24 hour period which are specifically involved with the learning process.
296 citations
TL;DR: The results indicate that the 24-hour pattern in electrical activity that is controlled by the molecular machinery of the SCN is substantially modified by afferent information from the central nervous system.
Abstract: The timing of sleep and wakefulness in mammals is governed by a sleep homeostatic process and by the circadian clock of the suprachiasmatic nucleus (SCN), which has a molecular basis for rhythm generation. By combining SCN electrical activity recordings with electroencephalogram (EEG) recordings in the same animal (the Wistar rat), we discovered that changes in vigilance states are paralleled by strong changes in SCN electrophysiological activity. During rapid eye movement (REM) sleep, neuronal activity in the SCN was elevated, and during non-REM (NREM) sleep, it was lowered. We also carried out selective sleep deprivation experiments to confirm that changes in SCN electrical activity are caused by changes in vigilance state. Our results indicate that the 24-hour pattern in electrical activity that is controlled by the molecular machinery of the SCN is substantially modified by afferent information from the central nervous system.
293 citations
TL;DR: This paper reviews the extensive literature describing ethanol's effects on the sleep of healthy normals and alcoholics and the newer literature that describes its interactive effects on daytime sleepiness, physiological functions during sleep, and sleep disorders.
292 citations