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Showing papers on "Nucleolar chromatin published in 1993"


Journal ArticleDOI
TL;DR: A hypothesis for chemical carcinogen induced condensation of nuclear and nucleolar chromatin is proposed and it is believed to be a result of cascade effects initiated by the inhibition of messenger RNA synthesis after exposure tochemical carcinogen in vivo.
Abstract: A hypothesis for chemical carcinogen induced condensation of nuclear and nucleolar chromatin is proposed. Chromatin condensation is believed to be a result of cascade effects initiated by the inhibition of messenger RNA synthesis after exposure to chemical carcinogen in vivo. Inhibition of messenger RNA synthesis leads to the loss of protein production, which in turn causes the dephosphorylation of histone H1 and triggers the condensation of chromatin in vivo.

5 citations