Topic
Nucleolus
About: Nucleolus is a research topic. Over the lifetime, 5873 publications have been published within this topic receiving 232435 citations. The topic is also known as: GO:0005730 & cell nucleolus.
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TL;DR: The present findings enable us to document the nucleolar localization signals in RPS19 and help define the phenotypic consequences of some mutations in R PS19 in DBA.
75 citations
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TL;DR: A novel mechanism for virus-induced host protein shut off in cardioviruses, whereby 2A helps to upregulate the synthesis of new and modified ribosomes that have an inherent preference for internal ribosomal entry site (IRES)-dependent viral genome translation over cap-dependent host mRNA translation, is observed.
75 citations
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TL;DR: A spontaneous chromosome fission in the plant Hypochoeris radicata has been characterized by Feulgen staining, in situ hybridization of the rDNA probe pTA71 and silver staining for active nucleolus organizing regions.
Abstract: A spontaneous chromosome fission in the plantHypochoeris radicata has been characterized by Feulgen staining,in situ hybridization of the rDNA probe pTA71 and silver staining for active nucleolus organizing regions. The parental acrocentric chromosome has no detectable ribosomal genes at the centromere, but both fission derivatives possess active NORs at their centric ends. In fission heterozygotes, pachytene configurations studied by synaptonemal complex spreading show that the ribosomal cistrons form short arms on each telocentric which pair together to form a triradial. The paired short arms are associated with the single nucleolus at pachytene. It is proposed that the origin and stabilization of the fission rearrangement involved transposition of rDNA from the nucleolus organizing region of chromosome 3 into the centromeric region of chromosome 1.
75 citations
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TL;DR: Changes in the morphology of cells during the regenerative tissue transformation of the pigmented epithelium of the iris into lens in the adult newt Triturus viridescens were studied in ultrathin sections using the electron microscope.
75 citations
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TL;DR: Results show that dosage compensation does not necessarily occur when the number of r RNA genes is reduced to below the haploid number, and suggests that there is little, if any, base sequence divergence among the highly reiterated rRNA genes.
75 citations